Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | TTK | P33981 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.38 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | ITK | Q08881 | 2/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.38 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158931 | 0.77 | ESR1 (0.46) | TP53LMNAHIF1A | |
| SCHEMBL9487343 | 0.76 | KDM4E (0.37) | KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL1230418 | 0.76 | PARP14 (0.43) | — | |
| SCHEMBL3638684 | 0.75 | KDM4E (0.49) | KDM4EIDO1TTKALDH1A1MAPK10 | |
| SCHEMBL3222732 | 0.75 | ALDH1A1 (0.30) | ALDH1A1MAPK1TSHRHSD17B10 | |
| SCHEMBL7131658 | 0.75 | — | — | |
| SCHEMBL6051921 | 0.73 | ALDH1A1 (0.41) | KDM4EALDH1A1GAAHPGDMAPK1 | |
| SCHEMBL6045243 | 0.72 | — | — | |
| SCHEMBL16210184 | 0.72 | KDM4E (0.45) | KDM4EIDO1TTKALDH1A1MAPK10 | |
| SCHEMBL5925960 | 0.72 | KDM4E (0.49) | KDM4EIDO1TTKALDH1A1MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673337-B1 | Arylalkylcarbamate derivatives, preparation method thereof and use of same in therapeutics | SANOFI SA (FR) | 2011-11-23 | — | — | EP | claimed |
| CN-101817784-A | Ethene derivatives and the pesticides that contains this derivative | NISSAN CHEMICAL IND LTD | 2010-09-01 | — | — | CN | claimed |
| CN-100591657-C | Indane acetic acid compound | BAYER PHARMACEUTICALS CORP | 2010-02-24 | — | — | CN | claimed |
| CN-100528850-C | Indane acetic acid derivatives, their use as medicaments, intermediates and processes for their preparation | BAYER AG (US) | 2009-08-19 | — | — | CN | claimed |
| CN-1763003-A | Ethylene derivatives and pesticides containing the same | NISSAN CHEMICAL IND LTD (JP) | 2006-04-26 | — | — | CN | claimed |
| CN-1227229-C | Ethylene derivatives and pesticides containing the same | NISSAN CHEMICAL IND LTD (JP) | 2005-11-16 | — | — | CN | claimed |
| CN-1192065-C | Oligo-methine colouring matter | CLARIANT FINANCE BVI LTD (GB) | 2005-03-09 | — | — | CN | claimed |
| CN-1558905-A | Indane acetic acid derivatives, their use as medicaments, intermediates and processes for their preparation | ������˹ҩƷ��˾ | 2004-12-29 | — | — | CN | claimed |
| CN-1546472-A | Pyridyl alkane acid amides as cytostatics and immunosupressives | ���ָ���ҩ�ɷ�����˾ | 2004-11-17 | — | — | CN | claimed |
| CN-1422262-A | 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors | ABBOTT GMBH & CO KG (DE) | 2003-06-04 | — | — | CN | claimed |
| CN-1390247-A | Oligo-methine colouring matter | CLARIANT FINANCE BVI LTD (VG) | 2003-01-08 | — | — | CN | claimed |
| CN-1216530-A | Ethylene derivatives and pesticides containing the same | NISSAN CHEMICAL IND LTD (JP) | 1999-05-12 | — | — | CN | claimed |
| CN-102471150-B | D1492 Liquid bisacylphosphine oxide photoinitiators and their use in radiation curable compositions | DSM IP ASSETS BV | 2014-05-07 | — | — | CN | disclosed |
| CN-101562975-B | Soil treatment agent or seed treatment agent containing quinoline compound or salt thereof as active ingredient, and method for controlling plant disease using same | SANKYO AGRO CO LTD | 2013-10-23 | — | — | CN | disclosed |
| CN-103347498-A | Pharmaceutical formulation of histone deacetylase inhibitor | SHAPE PHARMACEUTICALS INC | 2013-10-09 | — | — | CN | disclosed |
| CN-103342701-A | 2-Aminothiazole compound polycrystalline type as kinase inhibitors and preparation method thereof | AB SCIENCE | 2013-10-09 | — | — | CN | disclosed |
| CN-1290254-A | Sulfonamide derivatives process for producing the same and utilization thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-04-04 | — | — | CN | disclosed |
| CN-1216530-A | Ethylene derivatives and pesticides containing the same | NISSAN CHEMICAL IND LTD (JP) | 1999-05-12 | — | — | CN | disclosed |
| CN-1111241-A | Derivative of 2-imidazolin-5-one fungicide | RHONE POULENC AGROCHIMIE (FR) | 1995-11-08 | — | — | CN | disclosed |
| US-4840862-A | HIGH SENSITIVITY AND STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1989-06-20 | — | — | US | disclosed |