Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.49 |
| ▸ | TTK | P33981 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | ITK | Q08881 | 4/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | FLT1 | P17948 | 2/20 | 0.41 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.40 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623912 | 0.78 | METAP2 (0.35) | KDM4ETTKALDH1A1MAPK10GAA | |
| SCHEMBL6489268 | 0.76 | BCHE (0.40) | KDM4EALDH1A1GAAALPLHPGD | |
| SCHEMBL5925960 | 0.75 | KDM4E (0.49) | KDM4EIDO1TTKALDH1A1MAPK10 | |
| SCHEMBL1730792 | 0.75 | KDM4E (0.45) | KDM4EIDO1TTKALDH1A1MAPK10 | |
| SCHEMBL33442 | 0.75 | BCHE (0.47) | KDM4EIDO1ALDH1A1MAPK1NPC1 | |
| SCHEMBL31528475 | 0.75 | KDM4E (0.51) | KDM4EIDO1TTKALDH1A1MAPK10 | |
| SCHEMBL434158 | 0.74 | METAP2 (0.43) | ALDH1A1HPGDLRRK2FGFR1MAPK1 | |
| SCHEMBL2188838 | 0.74 | KDM4E (0.58) | KDM4EIDO1TTKALDH1A1MAPK10 | |
| SCHEMBL30316649 | 0.74 | KDM4E (0.58) | KDM4EIDO1TTKALDH1A1MAPK10 | |
| SCHEMBL30681831 | 0.74 | KDM4E (0.58) | KDM4EIDO1TTKALDH1A1MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008030120-A1 | A METHOD FOR THE FLUORESCENT DETECTION OF NITROREDUCTASE ACTIVITY USING NITRO-SUBSTITUTED AROMATIC COMPOUNDS | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-03-13 | — | — | WO | claimed |
| US-11999754-B2 | Ruthenium complexes and their use in olefin metathesis reactions | APEIRON SYNTHESIS S.A. (PL) | 2024-06-04 | — | — | US | disclosed |
| CN-110573502-B | Biocompatible modular tetrazine platform | 国家科学研究中心 | 2023-07-18 | — | — | CN | disclosed |
| EP-3820609-B1 | USE OF N-CHELATING RUTHENIUM COMPLEXES IN THE METATHESIS REACTION | APEIRON SYNTHESIS SA (PL) | 2023-06-28 | — | — | EP | disclosed |
| US-20210237045-A1 | USE OF N-CHELATING RUTHENIUM COMPLEXES IN THE METATHESIS REACTION | APEIRON SYNTHESIS S.A. (PL) | 2021-08-05 | — | — | US | disclosed |
| EP-3820609-A1 | <SMALLCAPS/>? ? ?N? ? ? ? ?USE OF-CHELATING RUTHENIUM COMPLEXES IN THE METATHESIS REACTION | Apeiron Synthesis S.A. (PL) | 2021-05-19 | — | — | EP | disclosed |
| US-20210101922-A1 | NOVEL RUTHENIUM COMPLEXES AND THEIR USE IN OLEFIN METATHESIS REACTIONS | APEIRON SYNTHESIS S.A. (PL) | 2021-04-08 | — | — | US | disclosed |
| EP-3781581-A1 | NOVEL RUTHENIUM COMPLEXES AND THEIR USE IN OLEFIN METATHESIS REACTIONS | Apeiron Synthesis S.A. (PL) | 2021-02-24 | — | — | EP | disclosed |
| WO-2019202509-A1 | NOVEL RUTHENIUM COMPLEXES AND THEIR USE IN OLEFIN METATHESIS REACTIONS | APEIRON SYNTHESIS S.A. (PL) | 2019-10-24 | — | — | WO | disclosed |
| EP-2718016-B1 | NEW COMPLEXES OF RUTHENIUM, METHOD FOR THEIR PREPARATION, AND THEIR APPLICATION IN OLEFIN METATHESIS REACTIONS | UMICORE AG & CO KG (DE) | 2019-08-14 | — | — | EP | disclosed |
| EP-2718016-A1 | NEW COMPLEXES OF RUTHENIUM, METHOD FOR THEIR PREPARATION, AND THEIR APPLICATION IN OLEFIN METATHESIS REACTIONS | Umicore AG & Co. KG (DE) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012168183-A1 | NEW COMPLEXES OF RUTHENIUM, METHOD FOR THEIR PREPARATION, AND THEIR APPLICATION IN OLEFIN METATHESIS REACTIONS | UMICORE AG & CO. KG (DE) | 2012-12-13 | — | — | WO | disclosed |
| EP-2155719-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | Wyeth LLC (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008147945-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210101922-A1 | NOVEL RUTHENIUM COMPLEXES AND THEIR USE IN OLEFIN METATHESIS REACTIONS | OPRM1, ADH1A, CYP2E1 | KDM4E 4822/4885IDO1 647/4885TTK 1313/4885 |
| US-20210237045-A1 | USE OF N-CHELATING RUTHENIUM COMPLEXES IN THE METATHESIS REACTION | CYC1, AP1M1, HNMT | KDM4E 4863/4885IDO1 767/4885TTK 1547/4885 |
| US-11999754-B2 | Ruthenium complexes and their use in olefin metathesis reactions | ADH1A, CYP2E1, OPRM1 | KDM4E 4806/4885IDO1 576/4885TTK 1497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.