Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17320114 | 0.91 | ALDH1A1 (0.39) | CNR2ALDH1A1THRBHPGDL3MBTL1 | |
| SCHEMBL17307936 | 0.82 | CNR1 (0.44) | CNR2CNR1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL17307943 | 0.80 | CNR2 (0.43) | CNR2CNR1ALDH1A1L3MBTL1CYP2C9 | |
| SCHEMBL17320113 | 0.74 | ADRB2 (0.39) | CNR2CNR1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL19223417 | 0.74 | UTS2R (0.40) | CNR2CNR1ALDH1A1HPGDKMT2A | |
| SCHEMBL19223359 | 0.73 | ADRB2 (0.38) | CNR2CNR1ALDH1A1HPGDKMT2A | |
| SCHEMBL822783 | 0.70 | ADRB2 (0.47) | ALDH1A1HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL12018016 | 0.70 | ADRB2 (0.62) | ALDH1A1HPGDKMT2AADRB2ADRB1 | |
| SCHEMBL5030862 | 0.69 | HRH3 (0.53) | ALDH1A1HPGDL3MBTL1KMT2AADRB2 | |
| SCHEMBL11617237 | 0.69 | PLK1 (0.48) | CNR2CNR1ALDH1A1THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9532931-B2 | Polysiloxane compound and dental materials that can be prepared from it | VOCO GMBH (DE) | 2017-01-03 | — | — | US | disclosed |
| US-20150342841-A1 | POLYSILOXANE COMPOUND AND DENTAL MATERIALS THAT CAN BE PREPARED FROM IT | VOCO GMBH (DE) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150342841-A1 | POLYSILOXANE COMPOUND AND DENTAL MATERIALS THAT CAN BE PREPARED FROM IT | SMCHD1, IPO5, IPO9 | CNR2 3737/4885CNR1 3171/4885ALDH1A1 1847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.