SCHEMBL173081

SCHEMBL173081

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nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.47
GLO1 Q04760 3/20 0.46
PTGS1 P23219 1/20 0.40
GSTK1 Q9Y2Q3 1/20 0.40
SELP P16109 1/20 0.38
PTPN1 P18031 2/20 0.36
BMP1 P13497 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14998213 0.84 GLP1R (0.57) GLP1R
SCHEMBL13267758 0.84 GLP1R (0.44) GLP1RGLO1PTGS1GSTK1
SCHEMBL172853 0.83 GLO1 (0.49) GLP1RGLO1PTGS1GSTK1BMP1
SCHEMBL16093420 0.81 GLP1R (0.54) GLP1RSELP
SCHEMBL26739923 0.78 GLP1R (0.50) GLP1RGLO1
SCHEMBL13165209 0.78 GLP1R (0.61) GLP1RSELP
SCHEMBL91017 0.78 GLP1R (0.61) GLP1RSELP
SCHEMBL15002730 0.78 GLP1R (0.61) GLP1RSELP
SCHEMBL13973930 0.78 GLP1R (0.61) GLP1RSELP
SCHEMBL73399 0.78 GLP1R (0.61) GLP1RSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120058932-A1 ACTIVE INGREDIENT-PEPTIDE CONSTRUCT FOR EXTRACELLULAR CONCENTRATION MAX PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2012-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120058932-A1 ACTIVE INGREDIENT-PEPTIDE CONSTRUCT FOR EXTRACELLULAR CONCENTRATION VIP, FIBP, MMP7 GLP1R 144/4885GLO1 2485/4885PTGS1 1350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.