Sugi Predict

Sugi Predict / Compounds / SCHEMBL17309679

SCHEMBL17309679

SCHEMBL17309679

C=C(C)C(=O)OCC(OC(=O)C(=C)C)(OC(=O)C(=C)C)OP(=O)(OC(COC(=O)C(=C)C)(OC(=O)C(=C)C)OC(=O)C(=C)C)OC(COC(=O)C(=C)C)(OC(=O)C(=C)C)OC(=O)C(=C)C

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ THRB P10828 1/20 0.38
▸ POLB P06746 1/20 0.32
▸ APEX1 P27695 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222088 0.90 TSHR (0.38) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL942089 0.87 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1
Acrylic Acid SCHEMBL21955709 0.82 TSHR (0.33) TSHRALDH1A1THRB
SCHEMBL15752774 0.81 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL15752863 0.80 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL15752920 0.77 THRB (0.41) TSHRALDH1A1THRB
SCHEMBL9558554 0.75 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL29780391 0.73 TSHR (0.45) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL10937523 0.73 TSHR (0.45) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL222087 0.73 ALDH1A1 (0.35) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10288782-B2 Infrared reflective film NITTO DENKO CORPORATION (JP) 2019-05-14 — — US disclosed
EP-3175982-B1 INFRARED RADIATION REFLECTING FILM NITTO DENKO CORP (JP) 2018-11-07 — — EP disclosed
EP-3175982-A1 INFRARED RADIATION REFLECTING FILM Nitto Denko Corporation (JP) 2017-06-07 — — EP disclosed
EP-2952343-B1 INFRARED RADIATION REFLECTING FILM NITTO DENKO CORP (JP) 2017-03-01 — — EP disclosed
US-20160003989-A1 INFRARED REFLECTIVE FILM NITTO DENKO CORPORATION (JP) 2016-01-07 — — US disclosed
EP-2952343-A1 INFRARED RADIATION REFLECTING FILM Nitto Denko Corporation (JP) 2015-12-09 — — EP disclosed