SCHEMBL17311331

SCHEMBL17311331

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C=Cc3ccc(CCC(=O)O)cc3)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 9/20 0.55
RAB9A P51151 1/20 0.51
KMT2A Q03164 1/20 0.51
ALDH1A1 P00352 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 2/20 0.43
KEAP1 Q14145 1/20 0.43
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
CYP4Z1 Q86W10 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
TRPM8 Q7Z2W7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17311329 1.00 FFAR1 (0.55) FFAR1RAB9AKMT2AALDH1A1L3MBTL1
SCHEMBL9495863 0.91 FFAR1 (0.65) FFAR1KMT2AALDH1A1L3MBTL1TDP1
SCHEMBL17321097 0.86 FFAR1 (0.59) FFAR1ALDH1A1L3MBTL1TDP1LMNA
SCHEMBL17311330 0.85 FFAR1 (0.49) FFAR1RAB9AKMT2AALDH1A1L3MBTL1
SCHEMBL17311328 0.85 FFAR1 (0.49) FFAR1RAB9AKMT2AALDH1A1L3MBTL1
SCHEMBL19380026 0.84 NFE2L2 (0.45) RAB9AKMT2ACTDSP1
SCHEMBL14732640 0.81 FFAR1 (0.67) FFAR1ALDH1A1L3MBTL1LMNAKEAP1
SCHEMBL169770 0.80 FFAR1 (0.79) FFAR1KMT2AALDH1A1L3MBTL1TDP1
SCHEMBL27698271 0.79 FFAR1 (0.76) FFAR1KMT2AALDH1A1L3MBTL1TDP1
SCHEMBL14200071 0.78 CYP3A4 (0.44) LMNACYP4Z1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9541848-B2 Electrophotographic photoreceptor Konica Minolta, Inc. (JP) 2017-01-10 US disclosed
US-20150355560-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR Konica Minolta, Inc. (JP) 2015-12-10 US disclosed