Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 11/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17583563 | 0.88 | NR3C2 (0.44) | NR3C2NR3C1 | |
| SCHEMBL30047470 | 0.88 | NR3C2 (0.44) | NR3C2NR3C1 | |
| Formic Acid SCHEMBL23857643 | 0.88 | NR3C2 (0.41) | NR3C2NR3C1KCNH2 | |
| SCHEMBL17311889 | 0.86 | NR3C2 (0.43) | NR3C2NR3C1KCNH2 | |
| SCHEMBL30048185 | 0.80 | NR3C2 (0.42) | NR3C2NR3C1 | |
| SCHEMBL23856697 | 0.80 | NR3C2 (0.42) | NR3C2NR3C1 | |
| SCHEMBL15875138 | 0.80 | NR3C2 (0.45) | NR3C2NR3C1KCNH2 | |
| SCHEMBL17311901 | 0.80 | PDE3B (0.33) | KCNH2 | |
| SCHEMBL15875778 | 0.78 | ALDH1A1 (0.49) | NR3C2NR3C1 | |
| Formic Acid SCHEMBL23857674 | 0.74 | KCNH2 (0.65) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487516-B2 | Antibacterial oxadiazolone derivatives | ACTELION PHARMACEUTICALS, LTD. (CH) | 2016-11-08 | — | — | US | disclosed |
| US-20150353547-A1 | Antibacterial Oxadiazolone Derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353547-A1 | Antibacterial Oxadiazolone Derivatives | OXA1L, PYM1, XDH | NR3C2 1013/4885NR3C1 2246/4885KCNH2 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.