Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10660120 | 1.00 | EPHX1 (0.61) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL66996 | 1.00 | EPHX1 (0.61) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL2848894 | 0.97 | EPHX1 (0.56) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL849367 | 0.85 | EPHX1 (0.42) | EPHX1ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL4454833 | 0.82 | EPHX1 (0.48) | EPHX1ALDH1A1DPP4SMN1; SMN2MAPT | |
| SCHEMBL13353720 | 0.80 | EPHX1 (0.42) | EPHX1ALDH1A1DPP4SMN1; SMN2MAPT | |
| SCHEMBL11197502 | 0.80 | EPHX1 (0.64) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL2837484 | 0.78 | EPHX1 (0.61) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL14456397 | 0.78 | EPHX1 (0.48) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL431289 | 0.78 | EPHX1 (0.48) | EPHX1ALDH1A1DPP4SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015187704-A1 | DGAT1 INHIBITION FOR TREATMENT OF DEMYELINATING INFLAMMATORY DISEASE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-12-10 | — | — | WO | disclosed |