SCHEMBL66996

SCHEMBL66996

O=C(O)C(C1CCCCC1)C1CCCCC1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 7/20 0.61
ALDH1A1 P00352 2/20 0.43
DPP4 P27487 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MAPT P10636 2/20 0.40
CYP3A4 P08684 2/20 0.40
KDM4E B2RXH2 1/20 0.40
EPHX2 P34913 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
TP53 P04637 2/20 0.39
MEN1 O00255 1/20 0.39
MITF O75030 1/20 0.39
LMNA P02545 1/20 0.39
ALOX15 P16050 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17316191 1.00 EPHX1 (0.61) EPHX1ALDH1A1DPP4SMN1; SMN2NPC1
SCHEMBL10660120 1.00 EPHX1 (0.61) EPHX1ALDH1A1DPP4SMN1; SMN2NPC1
SCHEMBL2848894 0.97 EPHX1 (0.56) EPHX1ALDH1A1DPP4SMN1; SMN2NPC1
SCHEMBL849367 0.85 EPHX1 (0.42) EPHX1ALDH1A1MAPTKDM4ETP53
SCHEMBL4454833 0.82 EPHX1 (0.48) EPHX1ALDH1A1DPP4SMN1; SMN2MAPT
SCHEMBL13353720 0.80 EPHX1 (0.42) EPHX1ALDH1A1DPP4SMN1; SMN2MAPT
SCHEMBL11197502 0.80 EPHX1 (0.64) EPHX1ALDH1A1DPP4SMN1; SMN2NPC1
SCHEMBL2837484 0.78 EPHX1 (0.61) EPHX1ALDH1A1DPP4SMN1; SMN2NPC1
SCHEMBL14456397 0.78 EPHX1 (0.48) EPHX1ALDH1A1DPP4SMN1; SMN2NPC1
SCHEMBL431289 0.78 EPHX1 (0.48) EPHX1ALDH1A1DPP4SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
EP-4637728-A1 COMPOSITION BioNTech Delivery Technologies GmbH (DE) 2025-10-29 EP claimed
US-20250231157-A1 METHOD FOR DETERMINING THE PARTITION OF NAPHTHENIC ACIDS FROM A PRODUCTION WATER MIMICKING SYSTEM AND MIMICKING SYSTEM PETRÓLEO BRASILEIRO S.A. – PETROBRAS (BR) 2025-07-17 US claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
WO-2024133635-A1 COMPOSITION BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) 2024-06-27 WO claimed
EP-3781697-A1 METHOD FOR DETERMINING CHEMICAL COMPOUNDS IN WASTE Renescience A/S (DK) 2021-02-24 EP claimed
WO-2019201765-A1 METHOD FOR DETERMINING CHEMICAL COMPOUNDS IN WASTE RENESCIENCE A/S (DK) 2019-10-24 WO claimed
CN-109456912-A The bacillus of one plant of degradable aphthenic acids and its application 东北师范大学 2019-03-12 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
CN-101050185-A Ion liquid of quaternaries of naphthenic acid INST OF PROCEDUE ENGINEERING C (CN) 2007-10-10 CN claimed
US-20070221507-A1 Anodizing Electrolytes Using A Dual Acid System For High Voltage Electrolytic Capacitor Anodes GREATBATCH LTD. (US) 2007-09-27 US claimed
EP-1826297-A2 Anodizing electrolytes using a dual acid system for high voltage electrolytic capacitor anodes Greatbatch Ltd. (US) 2007-08-29 EP claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS EPHX1 1402/4885ALDH1A1 3087/4885DPP4 853/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS EPHX1 1402/4885ALDH1A1 3087/4885DPP4 853/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 EPHX1 3259/4885ALDH1A1 1569/4885DPP4 2211/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 EPHX1 2835/4885ALDH1A1 1723/4885DPP4 1780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.