Sugi Predict

Sugi Predict / Compounds / SCHEMBL849367

SCHEMBL849367

SCHEMBL849367

O=C(O)C(C1CC1)C1CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX1 P07099 1/20 0.42
▸ CPN1 P15169 1/20 0.33
▸ CPB2 Q96IY4 1/20 0.33
▸ SLC1A2 P43004 2/20 0.32
▸ SLC1A1 P43005 2/20 0.32
▸ ALOX5 P09917 1/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ TSHR P16473 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ THRB P10828 1/20 0.32
▸ RECQL P46063 1/20 0.32
▸ ABCB11 O95342 1/20 0.30
▸ F2 P00734 1/20 0.30
▸ TP53 P04637 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ HPGD P15428 1/20 0.30
▸ ALOX15 P16050 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2848894 0.88 EPHX1 (0.56) EPHX1CPN1CPB2ALDH1A1LMNA
SCHEMBL28704681 0.87 EPHX1 (0.39) EPHX1CPB2SLC1A2SLC1A1ALOX5
SCHEMBL10660120 0.85 EPHX1 (0.61) EPHX1ALDH1A1LMNATP53KDM4E
SCHEMBL66996 0.85 EPHX1 (0.61) EPHX1ALDH1A1LMNATP53KDM4E
SCHEMBL17316191 0.85 EPHX1 (0.61) EPHX1ALDH1A1LMNATP53KDM4E
SCHEMBL4359285 0.78 AKR1C3 (0.33) ALDH1A1KDM4EMEN1MAPTALOX15
SCHEMBL31347862 0.76 EPHX1 (0.43) EPHX1ALOX5
SCHEMBL29106897 0.74 CPN1 (0.48) EPHX1CPN1CPB2TSHRLMNA
SCHEMBL5616701 0.73 CPN1 (0.33) EPHX1CPN1CPB2SLC1A2SLC1A1
SCHEMBL1645240 0.73 CPN1 (0.33) EPHX1CPN1CPB2SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250177383-A1 DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. 2025-06-05 — — US disclosed
US-20250122223-A1 HETEROCYCLIC COMPOUNDS AS UBIQUITIN SPECIFIC PROTEASE 7 INHIBITORS ALMAC DISCOVERY LIMITED (GB) 2025-04-17 — — US disclosed
EP-4482823-A1 DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF Dice Alpha, Inc. (US) 2025-01-01 — — EP disclosed
EP-4466072-A1 HETEROCYCLIC COMPOUNDS AS UBIQUITIN SPECIFIC PROTEASE 7 INHIBITORS Almac Discovery Limited (GB) 2024-11-27 — — EP disclosed
US-20240109898-A1 SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVES, COMPOSITIONS AND PHARMACEUTICAL USES THEREOF SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2024-04-04 — — US disclosed
EP-4282868-A1 SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) 2023-11-29 — — EP disclosed
CN-116761609-A Substituted pyrazolo [1,5-a ] pyrimidin-7-amine derivatives, compositions thereof and pharmaceutical uses thereof 上海海雁医药科技有限公司 2023-09-15 — — CN disclosed
WO-2023164057-A1 DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2023-08-31 — — WO disclosed
WO-2023139241-A1 HETEROCYCLIC COMPOUNDS AS UBIQUITIN SPECIFIC PROTEASE 7 INHIBITORS ALMAC DISCOVERY LIMITED (GB) 2023-07-27 — — WO disclosed
EP-3802535-B1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME AMGEN INC (US) 2022-12-14 — — EP disclosed
US-5447933-A Antidementia activity KYOWA HAKKO KOGYO CO., LTD. (JP) 1995-09-05 — — US disclosed
US-5342841-A Diuretics, renal protective agents, enzyme inhibitors KYOWA HAKKO KOGYO CO., LTD. (JP) 1994-08-30 — — US disclosed
EP-0560354-A1 Xanthine derivatives KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-09-15 — — EP disclosed
EP-0541120-A2 Xanthine derivatives for the treatment of dementia KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-05-12 — — EP disclosed
US-5068236-A Diuretics, renal protective agents and hypotensives KYOWA HAKKO KOGYO CO., LTD. (JP) 1991-11-26 — — US disclosed
EP-0386675-A2 Xanthine derivatives KYOWA HAKKO KOGYO CO., LTD. (JP) 1990-09-12 — — EP disclosed
EP-0128654-B1 GEM-DIAMINOALKANE DERIVED SWEETENERS CUMBERLAND PACKING CORPORATION (US) 1989-10-18 — — EP disclosed
EP-0242896-A2 Novel intermediates useful in the production of gem-diaminoalkane derived sweeteners CUMBERLAND PACKING CORPORATION (US) 1987-10-28 — — EP disclosed
US-4571345-A 1,1-Diaminoalkane derived sweeteners CUMBERLAND PACKING CORP. (US) 1986-02-18 — — US disclosed
EP-0128654-A2 Gem-diaminoalkane derived sweeteners CUMBERLAND PACKING CORPORATION (US) 1984-12-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109898-A1 SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVES, COMPOSITIONS AND PHARMACEUTICAL USES THEREOF CDK9, CDK19, CDK7 EPHX1 1546/4885CPN1 1493/4885CPB2 2796/4885
US-20250177383-A1 DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF IL17A, IL23R, IL2 EPHX1 1534/4885CPN1 4439/4885CPB2 3558/4885
US-20250122223-A1 HETEROCYCLIC COMPOUNDS AS UBIQUITIN SPECIFIC PROTEASE 7 INHIBITORS USP7, UBA7, SENP7 EPHX1 2706/4885CPN1 253/4885CPB2 813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.