Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | BRAF | P15056 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | APOBEC3B | Q9UH17 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | IDE | P14735 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18762149 | 0.82 | KMT2A (0.73) | APOBEC3GKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL18292329 | 0.81 | CSNK2A2 (0.74) | APOBEC3GKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL17318644 | 0.78 | NPC1 (0.70) | APOBEC3GKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL17318569 | 0.77 | NPC1 (0.65) | APOBEC3GKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL17318598 | 0.77 | NPC1 (0.65) | APOBEC3GKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL24599320 | 0.77 | CA1 (0.67) | KMT2AMEN1P2RX1LMNA | |
| SCHEMBL17318578 | 0.76 | NPC1 (0.72) | APOBEC3GNPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL13357696 | 0.76 | KDM4E (0.78) | APOBEC3GMAPK10MAPK8KMT2ANPC1 | |
| SCHEMBL24233115 | 0.76 | BLM (0.69) | MAPK10MAPK8KMT2ARAB9AMEN1 | |
| SCHEMBL24233015 | 0.76 | BLM (0.77) | MAPK10MAPK8KMT2ARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114060-A1 | NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-04-27 | — | — | US | disclosed |
| WO-2015187827-A1 | NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2015-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114060-A1 | NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME | ZC3HAV1, MAVS, EIF2AK2 | APOBEC3G 268/4885MAPK10 3689/4885MAPK8 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.