Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.62 |
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.57 |
| ▸ | APOBEC3B | Q9UH17 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17318577 | 0.84 | KDM4E (0.73) | KMT2AKDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL18292329 | 0.84 | CSNK2A2 (0.74) | KMT2AAPOBEC3GHSD17B10KDM4EALDH1A1 | |
| SCHEMBL17318712 | 0.84 | MCL1 (0.68) | KMT2AAPOBEC3GHSD17B10KDM4EALDH1A1 | |
| SCHEMBL17318569 | 0.82 | NPC1 (0.65) | KMT2AAPOBEC3GHSD17B10KDM4EALDH1A1 | |
| SCHEMBL17318656 | 0.82 | APOBEC3G (0.58) | KMT2AAPOBEC3GHSD17B10ALDH1A1NPSR1 | |
| SCHEMBL17318578 | 0.82 | NPC1 (0.72) | APOBEC3GHSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24232848 | 0.81 | MCL1 (0.74) | KMT2AKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8556554 | 0.81 | KMT2A (0.75) | KMT2AKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL17318644 | 0.81 | NPC1 (0.70) | KMT2AAPOBEC3GKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17318609 | 0.81 | ALDH1A1 (0.60) | KMT2AAPOBEC3GHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114060-A1 | NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114060-A1 | NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME | ZC3HAV1, MAVS, EIF2AK2 | KMT2A 2451/4885APOBEC3G 268/4885NT5E 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.