Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501483 | 0.80 | TSHR (0.55) | ALDH1A1CYP2C19KMT2AMEN1RAB9A | |
| SCHEMBL6509633 | 0.69 | L3MBTL1 (0.53) | ALDH1A1CYP2C19KMT2AMEN1RAB9A | |
| SCHEMBL6427337 | 0.69 | ALDH1A1 (0.50) | ALDH1A1CYP2C19KMT2AMEN1RAB9A | |
| SCHEMBL6430684 | 0.69 | ALDH1A1 (0.50) | ALDH1A1CYP2C19KMT2AMEN1RAB9A | |
| SCHEMBL6506802 | 0.67 | CYP2C19 (0.51) | ALDH1A1CYP2C19KMT2AMEN1L3MBTL1 | |
| SCHEMBL6425973 | 0.66 | KMT2A (0.48) | ALDH1A1CYP2C19KMT2AMEN1RAB9A | |
| SCHEMBL6426304 | 0.63 | EPHX2 (0.34) | ALDH1A1KMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL13105358 | 0.59 | MAPT (0.47) | ALDH1A1KMT2AMEN1POLBUSP2 | |
| SCHEMBL6502742 | 0.59 | TSHR (0.49) | ALDH1A1CYP2C19RAB9AL3MBTL1NPC1 | |
| SCHEMBL6425891 | 0.59 | TSHR (0.49) | ALDH1A1CYP2C19RAB9AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206125-B2 | Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF) | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |