Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN12 | Q05209 | 1/20 | 0.64 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.64 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MMP3 | P08254 | 2/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | MMP13 | P45452 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18837955 | 0.90 | ADAMTS5 (0.74) | PTPN12PTPN22ADAMTS5AKR1B1KMT2A | |
| SCHEMBL18837956 | 0.90 | ADAMTS5 (0.74) | PTPN12PTPN22ADAMTS5AKR1B1KMT2A | |
| SCHEMBL20558643 | 0.87 | PTPN12 (0.65) | PTPN12PTPN22ADAMTS5AKR1B1KMT2A | |
| SCHEMBL20558641 | 0.87 | PTPN12 (0.65) | PTPN12PTPN22ADAMTS5AKR1B1KMT2A | |
| SCHEMBL7050939 | 0.83 | PTPN12 (0.62) | PTPN12PTPN22AKR1B1KMT2AMMP3 | |
| SCHEMBL7050943 | 0.83 | PTPN12 (0.62) | PTPN12PTPN22AKR1B1KMT2AMMP3 | |
| SCHEMBL10492163 | 0.83 | PTPN12 (0.77) | PTPN12PTPN22AKR1B1KMT2AMMP3 | |
| SCHEMBL10492165 | 0.83 | PTPN12 (0.77) | PTPN12PTPN22AKR1B1KMT2AMMP3 | |
| SCHEMBL6886567 | 0.83 | PTPN12 (0.77) | PTPN12PTPN22AKR1B1KMT2AMMP3 | |
| SCHEMBL10491513 | 0.83 | PTPN12 (0.77) | PTPN12PTPN22AKR1B1KMT2AMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206412-B2 | Thioxothiazolidine inhibitors | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2015-12-08 | — | — | US | disclosed |