Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN12 | Q05209 | 1/20 | 0.62 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | MMP3 | P08254 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | MMP13 | P45452 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050943 | 1.00 | PTPN12 (0.62) | PTPN12PTPN22KMT2AAKR1B1MEN1 | |
| SCHEMBL17769188 | 0.94 | PTPN12 (0.59) | PTPN12PTPN22KMT2AAKR1B1MEN1 | |
| SCHEMBL20851927 | 0.92 | PTPN12 (0.57) | PTPN12PTPN22KMT2AAKR1B1MEN1 | |
| SCHEMBL20837934 | 0.90 | AKR1B1 (0.63) | KMT2AAKR1B1MEN1MAPTPSMD14 | |
| SCHEMBL17779690 | 0.90 | AKR1B1 (0.63) | KMT2AAKR1B1MEN1MAPTPSMD14 | |
| SCHEMBL7251137 | 0.88 | TAS2R14 (0.70) | KMT2AAKR1B1MEN1MAPTKDM4E | |
| SCHEMBL7251139 | 0.88 | TAS2R14 (0.70) | KMT2AAKR1B1MEN1MAPTKDM4E | |
| SCHEMBL17779687 | 0.87 | PTPN12 (0.65) | PTPN12PTPN22KMT2AAKR1B1MEN1 | |
| SCHEMBL20558641 | 0.87 | PTPN12 (0.65) | PTPN12PTPN22KMT2AAKR1B1MEN1 | |
| SCHEMBL20558643 | 0.87 | PTPN12 (0.65) | PTPN12PTPN22KMT2AAKR1B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590127-B2 | Split photoactive yellow protein complementation system and uses thereof | PARIS SCIENCES ET LETTRES (FR) | 2026-03-31 | — | — | US | claimed |
| US-20220169682-A1 | SPLIT PHOTOACTIVE YELLOW PROTEIN COMPLEMENTATION SYSTEM AND USES THEREOF | PARIS SCIENCES ET LETTRES (FR) | 2022-06-02 | — | — | US | claimed |
| EP-3947355-A1 | SPLIT PHOTOACTIVE YELLOW PROTEIN COMPLEMENTATION SYSTEM AND USES THEREOF | Paris Sciences et Lettres (FR) | 2022-02-09 | — | — | EP | claimed |
| WO-2020201538-A1 | SPLIT PHOTOACTIVE YELLOW PROTEIN COMPLEMENTATION SYSTEM AND USES THEREOF | PARIS SCIENCES ET LETTRES – QUARTIER LATIN (FR) | 2020-10-08 | — | — | WO | claimed |
| EP-3719007-A1 | SPLIT PHOTOACTIVE YELLOW PROTEIN COMPLEMENTATION SYSTEM AND USES THEREOF | Paris Sciences et Lettres - Quartier Latin (FR) | 2020-10-07 | — | — | EP | claimed |
| US-12590127-B2 | Split photoactive yellow protein complementation system and uses thereof | PARIS SCIENCES ET LETTRES (FR) | 2026-03-31 | — | — | US | disclosed |
| EP-4584590-A1 | PROXIMITY INDUCING SYSTEM AND USES THEREOF | SORBONNE UNIVERSITE (FR) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024052353-A1 | PROXIMITY INDUCING SYSTEM AND USES THEREOF | SORBONNE UNIVERSITE (FR) | 2024-03-14 | — | — | WO | disclosed |
| US-11584727-B2 | 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof | BSIM THERAPEUTICS, S.A. (PT) | 2023-02-21 | — | — | US | disclosed |
| US-11584727-B2 | 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof | BSIM THERAPEUTICS, S.A. (PT) | 2023-02-21 | — | — | US | disclosed |
| US-20220267286-A2 | 2-THIOXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF | BSIM THERAPEUTICS, S.A. (PT) | 2022-08-25 | — | — | US | disclosed |
| EP-4029859-A1 | 2-OXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF | BSIM THERAPEUTICS, S.A. (PT) | 2022-07-20 | — | — | EP | disclosed |
| EP-3404022-B1 | MEMBRANE-IMPERMEANT FLUOROGENIC CHROMOPHORES | PARIS SCIENCES LETTRES QUARTIER LATIN (FR) | 2020-10-07 | — | — | EP | disclosed |
| US-20200124611-A1 | MEMBRANE-IMPERMEANT FLUOROGENIC CHROMOPHORES | PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) | 2020-04-23 | — | — | US | disclosed |
| US-20200124611-A1 | MEMBRANE-IMPERMEANT FLUOROGENIC CHROMOPHORES | PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) | 2020-04-23 | — | — | US | disclosed |
| US-20190092737-A1 | 2-THIOXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF | BSIM2 - Biomolecular Simulations Lda. (PT) | 2019-03-28 | — | — | US | disclosed |
| US-20190092737-A1 | 2-THIOXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF | BSIM2 - Biomolecular Simulations Lda. (PT) | 2019-03-28 | — | — | US | disclosed |
| WO-2018211090-A1 | MEMBRANE-IMPERMEABLE FLUOROGENIC CHROMOPHORES | PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) | 2018-11-22 | — | — | WO | disclosed |
| EP-3404022-A1 | MEMBRANE-IMPERMEABLE FLUOROGENIC CHROMOPHORES | Paris Sciences et Lettres - Quartier Latin (FR) | 2018-11-21 | — | — | EP | disclosed |
| US-6673816-B1 | Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders | Esswein, Angelika (DE) | 2004-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267286-A2 | 2-THIOXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF | TTR, TTPA, MTPN | PTPN12 680/4885PTPN22 799/4885KMT2A 3693/4885 |
| US-20200124611-A1 | MEMBRANE-IMPERMEANT FLUOROGENIC CHROMOPHORES | QRFPR, BLVRB, IK | PTPN12 3374/4885PTPN22 3220/4885KMT2A 2506/4885 |
| US-20220169682-A1 | SPLIT PHOTOACTIVE YELLOW PROTEIN COMPLEMENTATION SYSTEM AND USES THEREOF | BLVRB, IK, HBG2 | PTPN12 1360/4885PTPN22 1028/4885KMT2A 1217/4885 |
| US-20190092737-A1 | 2-THIOXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF | TTR, TTPA, MTPN | PTPN12 815/4885PTPN22 647/4885KMT2A 3839/4885 |
| US-11584727-B2 | 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof | TTR, TTPA, MTPN | PTPN12 680/4885PTPN22 799/4885KMT2A 3693/4885 |
| US-12590127-B2 | Split photoactive yellow protein complementation system and uses thereof | BLVRB, HBG2, Q6ZSR9 | PTPN12 1567/4885PTPN22 1084/4885KMT2A 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.