Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17319256 | 0.89 | CTNNB1 (0.65) | AKR1B1MEN1KMT2APOLBMAPT | |
| SCHEMBL17319543 | 0.88 | POLB (0.60) | MEN1KMT2APOLB | |
| SCHEMBL10492318 | 0.83 | POLB (0.66) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL10492321 | 0.83 | POLB (0.66) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL1448003 | 0.83 | MEN1 (0.58) | AKR1B1MEN1KMT2APOLBMAPT | |
| SCHEMBL9736348 | 0.81 | POLB (0.51) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL10492260 | 0.80 | AKR1B1 (0.72) | AKR1B1MEN1KMT2APOLBMAPT | |
| SCHEMBL10492255 | 0.80 | AKR1B1 (0.72) | AKR1B1MEN1KMT2APOLBMAPT | |
| SCHEMBL18102937 | 0.80 | MEN1 (0.73) | MEN1KMT2APOLBMAPTKDM4E | |
| SCHEMBL10492194 | 0.80 | MMP3 (0.62) | AKR1B1MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206412-B2 | Thioxothiazolidine inhibitors | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2015-12-08 | — | — | US | disclosed |