Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.54 |
| ▸ | TUBB | P07437 | 3/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17320124 | 0.88 | PAX8 (0.52) | PAX8TUBB1LMNACYP2C9TUBB4A | |
| SCHEMBL18532941 | 0.87 | TUBB1 (0.57) | PAX8TUBB1LMNACYP2C9TUBB4A | |
| SCHEMBL17304591 | 0.86 | PAX8 (0.58) | PAX8TUBB1LMNACYP2C9TUBB4A | |
| SCHEMBL17304604 | 0.85 | PAX8 (0.59) | PAX8TUBB1LMNACYP2C9TUBB4A | |
| SCHEMBL17304596 | 0.84 | PAX8 (0.52) | PAX8TUBB1LMNACYP2C9TUBB4A | |
| SCHEMBL17304593 | 0.84 | LMNA (0.55) | PAX8TUBB1LMNACYP2C9TUBB4A | |
| SCHEMBL17304595 | 0.83 | PAX8 (0.54) | PAX8TUBB1LMNACYP2C9TUBB4A | |
| SCHEMBL18532915 | 0.82 | PAX8 (0.52) | PAX8TUBB1LMNACYP2C9TUBB4A | |
| SCHEMBL17304592 | 0.80 | PAX8 (0.53) | PAX8TUBB1LMNACYP2C9TUBB4A | |
| SCHEMBL17304603 | 0.78 | PAX8 (0.51) | PAX8TUBB1LMNACYP2C9TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2952501-A2 | Anti-cancer dibenzocycloheptane derivatives and a catalytic method for dibenzocycloheptane synthesis and allocolchicinoid synthesis | University of Windsor (CA) | 2015-12-09 | — | — | EP | disclosed |