Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 17/20 | 0.73 |
| ▸ | CYP27A1 | Q02318 | 2/20 | 0.53 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17320408 | 0.94 | ACHE (0.82) | ACHECYP27A1CYP24A1 | |
| Bromide SCHEMBL17313262 | 0.87 | ACHE (0.85) | ACHECYP27A1CYP24A1 | |
| SCHEMBL17320395 | 0.87 | ACHE (0.75) | ACHE | |
| Bromide SCHEMBL17313372 | 0.85 | ACHE (1.00) | ACHECYP27A1CYP24A1 | |
| SCHEMBL17320423 | 0.82 | ACHE (0.82) | ACHE | |
| SCHEMBL17320411 | 0.81 | ACHE (0.83) | ACHE | |
| SCHEMBL17320436 | 0.80 | ACHE (0.77) | ACHE | |
| SCHEMBL17320419 | 0.79 | ACHE (0.76) | ACHE | |
| SCHEMBL17320417 | 0.79 | ACHE (0.79) | ACHE | |
| SCHEMBL17320426 | 0.79 | ACHE (0.58) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376387-B2 | Oxidisable pyridine derivatives, their preparation and use as anti-alzheimer agents | INSA INST NAT DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2016-06-28 | — | — | US | disclosed |
| US-20150353493-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353493-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | CBR3, CBR1, CYB5R3 | ACHE 675/4885CYP27A1 164/4885CYP24A1 1704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.