Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956638 | 0.87 | NR1H2 (0.42) | USP2SMN1; SMN2ESR2PDK4NR1H2 | |
| SCHEMBL10305538 | 0.86 | USP2 (0.39) | USP2SMN1; SMN2ESR2PDK4NR1H2 | |
| SCHEMBL7534342 | 0.86 | USP2 (0.39) | USP2SMN1; SMN2ESR2PDK4NR1H2 | |
| SCHEMBL16086814 | 0.86 | FAAH (0.43) | USP2SMN1; SMN2ESR2PDK4NR1H2 | |
| SCHEMBL7987528 | 0.86 | NR1H2 (0.41) | USP2SMN1; SMN2ESR2PDK4NR1H2 | |
| SCHEMBL12566963 | 0.84 | PDK4 (0.48) | USP2SMN1; SMN2ESR2PDK4NR1H2 | |
| SCHEMBL29120639 | 0.84 | PDK4 (0.40) | USP2SMN1; SMN2ESR2PDK4NR1H2 | |
| SCHEMBL10587041 | 0.84 | NAMPT (0.38) | USP2SMN1; SMN2ESR2PDK4NR1H2 | |
| SCHEMBL22468365 | 0.83 | NR1H2 (0.39) | USP2SMN1; SMN2ESR2PDK4NR1H2 | |
| SCHEMBL3615685 | 0.83 | L3MBTL1 (0.44) | USP2SMN1; SMN2ESR2PDK4NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016008381-A1 | PYRIDINE DERIVATIVES AND ANTI-MYCOBACTERIAL USE THEREOF | 辰欣药业股份有限公司 | 2016-01-21 | — | — | WO | disclosed |
| WO-2015187684-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2015-12-10 | — | — | WO | disclosed |