Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14234095 | 0.92 | ALDH1A1 (0.62) | TP53ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL13438861 | 0.87 | SMN1; SMN2 (0.58) | TP53ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL4480468 | 0.86 | SMN1; SMN2 (0.61) | TP53ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL7901273 | 0.86 | SMN1; SMN2 (0.65) | TP53ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL12333479 | 0.85 | MEN1 (0.61) | TP53ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL4486004 | 0.85 | KMT2A (0.66) | TP53ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL10174738 | 0.85 | KMT2A (0.66) | TP53ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL27013485 | 0.83 | TP53 (0.51) | TP53ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL19605006 | 0.83 | HRH3 (0.59) | TP53ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL7901271 | 0.82 | RAB9A (0.67) | TP53ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015187684-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2015-12-10 | — | — | WO | disclosed |