Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402795 | 0.85 | HDAC4 (0.42) | HDAC4 | |
| SCHEMBL803450 | 0.84 | HDAC4 (0.40) | HDAC4 | |
| SCHEMBL803048 | 0.77 | HDAC4 (0.45) | HDAC4 | |
| SCHEMBL802995 | 0.77 | HDAC4 (0.41) | HDAC4 | |
| SCHEMBL25450843 | 0.74 | CA2 (0.36) | — | |
| SCHEMBL254224 | 0.68 | — | — | |
| SCHEMBL803639 | 0.68 | GRIN1 (0.40) | HDAC4 | |
| SCHEMBL16132806 | 0.68 | HDAC4 (0.70) | HDAC4HDAC9 | |
| SCHEMBL2276508 | 0.68 | SIGMAR1 (0.51) | HDAC4HDAC9 | |
| SCHEMBL16111974 | 0.67 | HDAC4 (0.68) | HDAC4HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150353495-A1 | NICOTINAMIDES AS JAK KINASE MODULATORS | ALEXION PHARMACEUTICALS, INC. | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353495-A1 | NICOTINAMIDES AS JAK KINASE MODULATORS | JAK2, JAK1, NADK | HDAC4 866/4885HDAC9 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.