Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 4/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622104 | 0.97 | — | — | |
| SCHEMBL6377644 | 0.86 | TDP1 (0.32) | MEN1KMT2A | |
| SCHEMBL5940287 | 0.86 | TDP1 (0.32) | MEN1KMT2A | |
| SCHEMBL1862347 | 0.85 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL1865535 | 0.85 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| Methylsulfanylmethane SCHEMBL1864248 | 0.83 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| Methylsulfanylmethane SCHEMBL1861188 | 0.83 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| Methylsulfanylmethane SCHEMBL1867910 | 0.83 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| Methylsulfanylmethane SCHEMBL1867145 | 0.83 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| Tetraethylene Glycol SCHEMBL28263633 | 0.83 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180009829-A1 | GOLD NANOPARTICLES AND METHODS OF MAKING AND USING GOLD NANOPARTICLES | UNIVERSITY OF OREGON (US) | 2018-01-11 | — | — | US | disclosed |
| US-9771380-B2 | Gold nanoparticles and methods of making and using gold nanoparticles | UNIVERSITY OF OREGON (US) | 2017-09-26 | — | — | US | disclosed |
| US-20150353580-A1 | GOLD NANOPARTICLES AND METHODS OF MAKING AND USING GOLD NANOPARTICLES | UNIVERSITY OF OREGON | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180009829-A1 | GOLD NANOPARTICLES AND METHODS OF MAKING AND USING GOLD NANOPARTICLES | MPO, SPR, CD63 | MEN1 4530/4885KMT2A 2923/4885TSHR 1683/4885 |
| US-20150353580-A1 | GOLD NANOPARTICLES AND METHODS OF MAKING AND USING GOLD NANOPARTICLES | MPO, SPR, CD63 | MEN1 4530/4885KMT2A 2923/4885TSHR 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.