Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101535 | 0.85 | HTT (0.61) | HTTHIF1AKDM4EMAPK1TDP1 | |
| SCHEMBL14595232 | 0.83 | HTT (0.61) | HTTHIF1AKDM4EMAPK1AR | |
| SCHEMBL18120597 | 0.81 | KDM4E (0.71) | HTTHIF1AKDM4EMAPK1TDP1 | |
| SCHEMBL1101566 | 0.80 | HTT (0.55) | HTTHIF1AKDM4EMAPK1TDP1 | |
| SCHEMBL1101870 | 0.79 | HTT (0.60) | HTTHIF1AKDM4EMAPK1TDP1 | |
| SCHEMBL11650773 | 0.78 | HTT (0.68) | HTTHIF1AKDM4EMAPK1TDP1 | |
| SCHEMBL22745504 | 0.77 | HTT (0.52) | HTTHIF1AKDM4EMAPK1TDP1 | |
| SCHEMBL1708894 | 0.77 | HTT (0.65) | HTTHIF1AKDM4EMAPK1AR | |
| SCHEMBL14196580 | 0.76 | HTT (0.56) | HTTHIF1AKDM4EMAPK1TDP1 | |
| SCHEMBL801366 | 0.76 | HTT (0.60) | HTTHIF1AKDM4EMAPK1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244550-A1 | HYBRID EPOXY-AMINE HYDROXYURETHANE-GRAFTED POLYMER | POLYMATE LTD (IL) | 2016-08-25 | — | — | US | disclosed |
| US-20160244563-A1 | HYBRID EPOXY-AMINE HYDROXYURETHANE-GRAFTED POLYMER | POLYMATE LTD (IL) | 2016-08-25 | — | — | US | disclosed |
| US-20160244551-A1 | HYBRID EPOXY-AMINE HYDROXYURETHANE-GRAFTED POLYMER | POLYMATE LTD (IL) | 2016-08-25 | — | — | US | disclosed |
| US-20150353683-A1 | HYBRID EPOXY-AMINE HYDROXYURETHANE-GRAFTED POLYMER | NANOTECH INDUSTRIES, INC. | 2015-12-10 | — | — | US | disclosed |