SCHEMBL1101870

SCHEMBL1101870

COc1ccc(C(C)(C)c2ccc(OCC(O)CN(CCN)CCN)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 1/20 0.60
▸ HIF1A Q16665 1/20 0.60
▸ AR P10275 1/20 0.49
▸ MAPT P10636 3/20 0.48
▸ GAA P10253 3/20 0.48
▸ KDM4E B2RXH2 2/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ KMT2A Q03164 3/20 0.47
▸ MEN1 O00255 2/20 0.47
▸ ALDH1A1 P00352 4/20 0.47
▸ LMNA P02545 1/20 0.47
▸ TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1101566 0.95 HTT (0.55) HTTHIF1AARMAPTGAA
SCHEMBL10077719 0.90 HTT (0.60) HTTHIF1AARGAAKDM4E
SCHEMBL1101535 0.89 HTT (0.61) HTTHIF1AARMAPTGAA
SCHEMBL25085460 0.83 ALDH1A1 (0.58) HTTHIF1AARMAPTGAA
SCHEMBL1101533 0.83 HTT (0.58) HTTHIF1AARMAPTGAA
SCHEMBL1708894 0.82 HTT (0.65) HTTHIF1AARMAPTGAA
SCHEMBL18120597 0.82 KDM4E (0.71) HTTHIF1AARGAAKDM4E
SCHEMBL17324142 0.79 HTT (0.53) HTTHIF1AARMAPTGAA
SCHEMBL14595232 0.79 HTT (0.61) HTTHIF1AARMAPTGAA
SCHEMBL24083864 0.79 AR (0.67) HTTHIF1AARGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120160685-A1 COATING LINE AND PROCESS FOR FORMING A MULTILAYER COMPONENT COATING ON A SUBSTRATE PPG INDUSTRIES OHIO, INC. (US) 2012-06-28 — — US disclosed
US-8152982-B2 Coating line and process for forming a multilayer component coating on a substrate PURDY SEAN (US) 2012-04-10 — — US disclosed
US-20090173633-A1 COATING LINE AND PROCESS FOR FORMING A MULTILAYER COMPONENT COATING ON A SUBSTRATE PPG INDUSTRIES OHIO, INC. (US) 2009-07-09 — — US disclosed
US-7531074-B2 Curing electrodeposition coating layer; dehydrating aqueous curable base coating layer; pigment-free; automobile clear coats; wear and corrosion resistance PPG INDUSTRIES OHIO, INC. (US) 2009-05-12 — — US disclosed
US-20070278104-A9 Coating line and process for forming a multilayer composite coating on a substrate PURDY SEAN 2007-12-06 — — US disclosed
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