SCHEMBL173250

SCHEMBL173250

C=CCOC(=O)CC(O)(CC(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
PKM P14618 1/20 0.36
NPSR1 Q6W5P4 1/20 0.33
CYP3A4 P08684 1/20 0.33
CASP1 P29466 2/20 0.32
KDM4E B2RXH2 3/20 0.32
MAPT P10636 2/20 0.32
LMNA P02545 2/20 0.32
ALOX15 P16050 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
GAA P10253 1/20 0.31
SLC13A5 Q86YT5 3/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL8925075 0.97 ALDH1A1 (0.50) ALDH1A1TSHRTDP1SMN1; SMN2PKM
Ethylene Glycol SCHEMBL28512446 0.95 ALDH1A1 (0.48) ALDH1A1TSHRTDP1SMN1; SMN2PKM
SCHEMBL2576139 0.94 ALDH1A1 (0.43) ALDH1A1TSHRTDP1SMN1; SMN2PKM
SCHEMBL1538354 0.88 ALDH1A1 (0.38) ALDH1A1TSHRTDP1SMN1; SMN2PKM
SCHEMBL2576138 0.88 ALDH1A1 (0.38) ALDH1A1TSHRTDP1SMN1; SMN2PKM
SCHEMBL8603567 0.86 TSHR (0.44) ALDH1A1TSHRTDP1SMN1; SMN2PKM
SCHEMBL28476458 0.85 ALDH1A1 (0.46) ALDH1A1TSHRTDP1CYP3A4KDM4E
SCHEMBL8165120 0.84 ALDH1A1 (0.56) ALDH1A1TSHRKDM4EMAPTLMNA
Ethylene Glycol SCHEMBL1071330 0.83 TSHR (0.35) ALDH1A1TSHRTDP1SMN1; SMN2PKM
Ethylene Glycol SCHEMBL907989 0.83 TSHR (0.35) ALDH1A1TSHRTDP1SMN1; SMN2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4646 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032260-B2 Optically transparent polymer electrolyte films DELSTAR TECHNOLOGIES, INC. 2024-07-09 US claimed
EP-3990037-B1 LAYERED COLLAGEN DRESSING WITH EXTENDED BACTERIA AND BIOFILM REDUCING CAPABILITIES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-06-19 EP claimed
US-20240189236-A1 COMPOSITION COMPRISING A (METH)ACRYLATE COPOLYMER, AN ALKALI OR AMMONIUM SALT OF A SATURATED ALIPHATIC MONOCARBOXYLIC ACID AND SPECIFIC GLIDANTS EVONIK OPERATIONS GMBH (DE) 2024-06-13 US claimed
EP-4381004-A2 CELLULOSE NANOFIBER (CNF) STABILIZED MEMBRANES AND METHODS OF MAKING THEREOF University of Maine System Board of Trustees (US) 2024-06-12 EP claimed
WO-2024115237-A1 COMPOSTABLE BIOPLASTIC FILMS QINETIQ LIMITED (GB) 2024-06-06 WO claimed
WO-2024115238-A1 COMPOSITE BIOPLASTIC MATERIAL QINETIQ LIMITED (GB) 2024-06-06 WO claimed
EP-4366708-A1 HARD SHELL CAPSULES HAVING IMPROVED COLON RELEASE Evonik Operations GmbH (DE) 2024-05-15 EP claimed
EP-4366710-A1 COMPOSITION COMPRISING A (METH)ACRYLATE COPOLYMER, AN ALKALI OR AMMONIUM SALT OF A SATURATED ALIPHATIC MONOCARBOXYLIC ACID AND SPECIFIC GLIDANTS Evonik Operations GmbH (DE) 2024-05-15 EP claimed
US-11980692-B2 Process for preparing a coated hard shell capsule EVONIK OPERATIONS GMBH (DE) 2024-05-14 US claimed
EP-4346779-A1 HARD SHELL CAPSULES WITH MODIFIED RELEASE COATING Evonik Operations GmbH (DE) 2024-04-10 EP claimed
US-5399556-A Complex of ranitidine and a zinc citrate; gastrointestinal disorders, peptic ulcers GLAXO GROUP LTD. (GB) 1995-03-21 US claimed
EP-0635260-A1 Oil-based transparent gels ENICHEM AUGUSTA INDUSTRIALE S.r.l. (IT) 1995-01-25 EP claimed
US-5296236-A Coated microgranules RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) 1994-03-22 US claimed
US-5221688-A Gastrointestinal disorders GLAXO GROUP LIMITED (GB) 1993-06-22 US claimed
EP-0454469-A1 Carboxylic acid derivatives GLAXO GROUP LIMITED (GB) 1991-10-30 EP claimed
EP-0454449-A1 Carboxylic acid derivatives GLAXO GROUP LIMITED (GB) 1991-10-30 EP claimed
EP-0445949-A1 Pharmaceutical compositions comprising carboxylic acid derivatives GLAXO GROUP LIMITED (GB) 1991-09-11 EP claimed
EP-0433010-A2 Polycarboxylate compounds and detergent compositions containing them UNILEVER PLC (GB) 1991-06-19 EP claimed
US-4609403-A MICRODISPERSION OF GAS BUBBLES IN WALLS WARNER-LAMBERT COMPANY (US) 1986-09-02 US claimed
US-4028065-A HYDROCARBON ESTERS OF CITRIC ACID ADDITIVE, IMPROVING OCTANE RATING OF GASOLINE STANDARD OIL COMPANY (US) 1977-06-07 US claimed