Ethylene Glycol

Ethylene Glycol

SCHEMBL28512446

C=CCOC(=O)CC(O)(CC(=O)O)C(=O)O.OCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 1/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31
CYP3A4 P08684 1/20 0.31
CASP1 P29466 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173250 0.95 ALDH1A1 (0.54) ALDH1A1TSHRTDP1PKMSMN1; SMN2
Ammonia Solution, Strong SCHEMBL8925075 0.92 ALDH1A1 (0.50) ALDH1A1TSHRTDP1PKMSMN1; SMN2
SCHEMBL2576139 0.90 ALDH1A1 (0.43) ALDH1A1TSHRTDP1PKMSMN1; SMN2
Ethylene Glycol SCHEMBL1071330 0.89 TSHR (0.35) ALDH1A1TSHRTDP1PKMSMN1; SMN2
Ethylene Glycol SCHEMBL907989 0.89 TSHR (0.35) ALDH1A1TSHRTDP1PKMSMN1; SMN2
Ethylene Glycol SCHEMBL10938553 0.85 ALDH1A1 (0.43) ALDH1A1
Citric Acid SCHEMBL28485608 0.85 ALDH1A1 (0.54) ALDH1A1TSHRKDM4ELMNAMAPT
SCHEMBL2576138 0.83 ALDH1A1 (0.38) ALDH1A1TSHRTDP1PKMSMN1; SMN2
SCHEMBL1538354 0.83 ALDH1A1 (0.38) ALDH1A1TSHRTDP1PKMSMN1; SMN2
SCHEMBL8603567 0.82 TSHR (0.44) ALDH1A1TSHRTDP1PKMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108289801-B Oral care gel 高露洁-棕榄公司 2021-01-26 CN disclosed