Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | FURIN | P09958 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12290183 | 0.98 | MAPT (0.60) | MAPTALDH1A1SMN1; SMN2NPC1FURIN | |
| SCHEMBL18601998 | 0.94 | MAPT (0.62) | MAPTALDH1A1SMN1; SMN2NPC1FURIN | |
| SCHEMBL12210902 | 0.87 | MAPT (0.66) | MAPTALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL20543330 | 0.85 | MAPT (0.72) | MAPTALDH1A1SMN1; SMN2NPC1FURIN | |
| SCHEMBL18602018 | 0.85 | THRA (0.54) | ALDH1A1FURINHDAC3HDAC1HDAC2 | |
| SCHEMBL15480462 | 0.85 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2NPC1FURIN | |
| SCHEMBL21693591 | 0.84 | HDAC1 (0.71) | MAPTALDH1A1SMN1; SMN2NPC1HDAC3 | |
| SCHEMBL18601989 | 0.84 | THRA (0.56) | ALDH1A1FURINHDAC3HDAC1HDAC2 | |
| SCHEMBL12212697 | 0.83 | MAPT (0.60) | MAPTALDH1A1SMN1; SMN2NPC1FURIN | |
| SCHEMBL27892102 | 0.83 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2NPC1FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3152226-B1 | MODIFIED CYCLOPENTAPEPTIDES AND USES THEREOF | UNIV MUENCHEN TECH (DE) | 2019-05-29 | — | — | EP | disclosed |
| EP-2560690-B1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2017-03-08 | — | — | EP | disclosed |
| WO-2015185162-A1 | MODIFIED CYCLOPENTAPEPTIDES AND USES THEREOF | Technische Universität München (DE) | 2015-12-10 | — | — | WO | disclosed |