Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18601989 | 0.99 | THRA (0.56) | THRATHRBALDH1A1HDAC3HDAC1 | |
| SCHEMBL18602132 | 0.87 | THRA (0.53) | THRATHRBALDH1A1HDAC3HDAC1 | |
| SCHEMBL17328296 | 0.85 | MAPT (0.59) | ALDH1A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL12290183 | 0.84 | MAPT (0.60) | ALDH1A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL4569791 | 0.83 | THRA (0.65) | THRATHRBALDH1A1HDAC3HDAC1 | |
| SCHEMBL18602310 | 0.81 | THRA (0.55) | THRATHRBALDH1A1HDAC1HDAC2 | |
| SCHEMBL15127695 | 0.80 | TP53 (0.68) | THRATHRBALDH1A1HDAC3HDAC1 | |
| SCHEMBL9517500 | 0.79 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AATM | |
| SCHEMBL18601998 | 0.79 | MAPT (0.62) | ALDH1A1LTA4HFURIN | |
| SCHEMBL21033719 | 0.79 | CA1 (0.55) | THRATHRBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3152226-B1 | MODIFIED CYCLOPENTAPEPTIDES AND USES THEREOF | UNIV MUENCHEN TECH (DE) | 2019-05-29 | — | — | EP | disclosed |
| EP-2560690-B1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2017-03-08 | — | — | EP | disclosed |