Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17328707 | 1.00 | METAP2 (0.62) | METAP2DOCK5 | |
| SCHEMBL17328642 | 1.00 | METAP2 (0.62) | METAP2DOCK5 | |
| SCHEMBL17328614 | 0.84 | METAP2 (0.63) | METAP2 | |
| SCHEMBL15367309 | 0.84 | METAP2 (0.63) | METAP2 | |
| SCHEMBL15367315 | 0.84 | METAP2 (0.63) | METAP2 | |
| SCHEMBL12469451 | 0.84 | METAP2 (0.65) | METAP2 | |
| SCHEMBL15367119 | 0.84 | METAP2 (0.65) | METAP2 | |
| SCHEMBL12469702 | 0.84 | METAP2 (0.65) | METAP2 | |
| SCHEMBL17328699 | 0.83 | HDAC11 (0.52) | METAP2 | |
| SCHEMBL17328698 | 0.83 | HDAC11 (0.52) | METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627631-B1 | PYRROLIDINONES AS METAP2 INHIBITORS | MERCK PATENT GMBH (DE) | 2015-12-16 | — | — | EP | claimed |