Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CAD | P27708 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1731339 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL89146 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL22144315 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL1415615 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL9834260 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL9753730 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL6157334 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL23255902 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL6581296 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL10867163 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110066835-B | Application of lipase in resolution of racemic ethyl 2-bromoisovalerate | 浙江工业大学 | 2020-12-25 | — | — | CN | disclosed |
| EP-1852433-B1 | CARBAZOLE DERIVATIVE, SOLVATE THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ZERIA PHARM CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| CN-101048402-B | Carbazole derivative, solvate thereof, or pharmaceutically acceptable salt thereof | ZERIA PHARM CO LTD | 2011-11-09 | — | — | CN | disclosed |
| EP-1852433-A1 | CARBAZOLE DERIVATIVE, SOLVATE THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Zeria Pharmaceutical Co., Ltd. (JP) | 2007-11-07 | — | — | EP | disclosed |