Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CAD | P27708 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1733288 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL1731339 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL22144315 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL1415615 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL9834260 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL9753730 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL6157334 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL23255902 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL6581296 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL10867163 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 664 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115959993-B | Synthesis method of 2-aryl propionic acid compound | 山东中医药大学 | 2025-01-07 | — | — | CN | claimed |
| CN-116283648-B | Substituted benzene acryloyl or benzene propionyl phenethylamine compound and preparation method and application thereof | 中国医学科学院药用植物研究所 | 2024-03-19 | — | — | CN | claimed |
| CN-116283648-A | Substituted benzene acryloyl or benzene propionyl phenethylamine compound and preparation method and application thereof | 中国医学科学院药用植物研究所 | 2023-06-23 | — | — | CN | claimed |
| CN-115959993-A | Synthetic method of 2-aryl propionic acid compound | 山东中医药大学 | 2023-04-14 | — | — | CN | claimed |
| CN-107560897-B | Single-person adjustable vertical water sampling method | 浙江海洋大学 | 2020-06-16 | — | — | CN | claimed |
| CN-110066835-A | A kind of application of lipase in resolution of racemic 2- bromo ethyl isovalerate | 浙江工业大学 | 2019-07-30 | — | — | CN | claimed |
| EP-2399902-B1 | PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANO SUCCINIC ACID DIESTERS | CHINA PETROLEUM & CHEMICAL (CN) | 2014-11-26 | — | — | EP | claimed |
| US-8669392-B2 | Process for preparing 2,3-di-non-straight-alkyl-2-cyanosuccinic acid diesters | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2014-03-11 | — | — | US | claimed |
| US-20120046490-A1 | PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANOSUCCINIC ACID DIESTERS | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2012-02-23 | — | — | US | claimed |
| EP-2399902-A1 | PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANO SUCCINIC ACID DIESTERS | China Petroleum & Chemical Corporation (CN) | 2011-12-28 | — | — | EP | claimed |
| US-20260144788-A1 | COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF | UBIX THERAPEUTICS, INC. (KR) | 2026-05-28 | — | — | US | disclosed |
| US-12617802-B2 | Sulfonimidamide compounds as NLRP3 modulators | GENENTECH, INC. (US) | 2026-05-05 | — | — | US | disclosed |
| WO-2026090330-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| EP-4711368-A1 | AZEPINE COMPOUND, AND COMPOSITION AND USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2026-03-18 | — | — | EP | disclosed |
| EP-3773573-B1 | ANTAGONISTS OF HUMAN INTEGRIN (ALPHA4)(BETA7) | MORPHIC THERAPEUTIC INC (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-0066217-A1 | Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, processes for the preparation thereof and the use thereof for combating weeds | ROHM AND HAAS COMPANY (US) | 1982-12-08 | — | — | EP | disclosed |
| US-4304788-A | ANTIARTHRITIC AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-12-08 | — | — | US | disclosed |
| EP-0020052-A1 | Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, processes for the preparation thereof and the use thereof for combating weeds | ROHM AND HAAS COMPANY (US) | 1980-12-10 | — | — | EP | disclosed |
| US-4089672-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-05-16 | — | — | US | disclosed |
| US-4084955-A | 1-CARBOXYALKYL-DI- AND TRIHALOPYRAZOLES, HERBICIDES | THE UPJOHN COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046490-A1 | PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANOSUCCINIC ACID DIESTERS | ACMSD, ADSL, CNDP2 | ALDH1A1 1240/4885TRPA1 4644/4885LMNA 479/4885 |
| US-20260144788-A1 | COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF | PTPN6, PTPN1, PTPN11 | ALDH1A1 3337/4885TRPA1 2946/4885LMNA 4730/4885 |
| US-12617802-B2 | Sulfonimidamide compounds as NLRP3 modulators | NLRP3, NLRP1, PYCARD | ALDH1A1 2022/4885TRPA1 53/4885LMNA 2411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.