Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2595803 | 0.76 | S1PR1 (0.68) | S1PR1S1PR5ALOX15PLK1ADORA2A | |
| SCHEMBL19836179 | 0.74 | S1PR1 (0.41) | S1PR1S1PR3CYP2C9CYP2C19CNR1 | |
| SCHEMBL29808202 | 0.72 | NOTUM (0.50) | S1PR1S1PR5ALOX15HDAC4HDAC1 | |
| SCHEMBL2106230 | 0.72 | NOTUM (0.50) | S1PR1S1PR5ALOX15HDAC4HDAC1 | |
| SCHEMBL436150 | 0.71 | S1PR1 (1.00) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL29389224 | 0.71 | S1PR1 (1.00) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL13416529 | 0.69 | S1PR1 (1.00) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL5988206 | 0.68 | S1PR1 (0.69) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL29695849 | 0.67 | S1PR1 (0.82) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL30207 | 0.66 | PPARA (0.46) | ADORA2AADORA1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078270-B2 | Use of negative functional modulators of erythropoietin for therapy | ANDREMACON S.R.L. (IT) | 2021-08-03 | — | — | US | claimed |
| EP-3154580-B1 | USE OF NEGATIVE FUNCTIONAL MODULATORS OF ERYTHROPOIETIN FOR THERAPY | ANDREMACON S R L (IT) | 2020-03-25 | — | — | EP | claimed |
| US-20170114132-A1 | USE OF NEGATIVE FUNCTIONAL MODULATORS OF ERYTHROPOIETIN FOR THERAPY | ANDREMACON S.R.L. (IT) | 2017-04-27 | — | — | US | claimed |
| EP-3154580-A1 | USE OF NEGATIVE FUNCTIONAL MODULATORS OF ERYTHROPOIETIN FOR THERAPY | Andremacon S.r.l. (IT) | 2017-04-19 | — | — | EP | claimed |
| WO-2015189813-A1 | USE OF NEGATIVE FUNCTIONAL MODULATORS OF ERYTHROPOIETIN FOR THERAPY | ANDREMACON S.R.L. (IT) | 2015-12-17 | — | — | WO | claimed |
| US-20250333489-A1 | EPO VARIANTS AND MODULATORS | ANDREMACON S.R.L. (IT) | 2025-10-30 | — | — | US | disclosed |
| CN-117940451-A | EPO variants and modulators | 安德烈马肯有限公司 | 2024-04-26 | — | — | CN | disclosed |
| EP-4355425-A1 | EPO VARIANTS AND MODULATORS | Andremacon S.r.l. (IT) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022263880-A1 | EPO VARIANTS AND MODULATORS | ANDREMACON S.R.L. (IT) | 2022-12-22 | — | — | WO | disclosed |
| US-20210340241-A1 | USE OF NEGATIVE FUNCTIONAL MODULATORS OF ERYTHROPOIETIN FOR THERAPY | ANDREMACON S.R.L. (IT) | 2021-11-04 | — | — | US | disclosed |
| US-11078270-B2 | Use of negative functional modulators of erythropoietin for therapy | ANDREMACON S.R.L. (IT) | 2021-08-03 | — | — | US | disclosed |
| EP-3154580-B1 | USE OF NEGATIVE FUNCTIONAL MODULATORS OF ERYTHROPOIETIN FOR THERAPY | ANDREMACON S R L (IT) | 2020-03-25 | — | — | EP | disclosed |
| US-20170114132-A1 | USE OF NEGATIVE FUNCTIONAL MODULATORS OF ERYTHROPOIETIN FOR THERAPY | ANDREMACON S.R.L. (IT) | 2017-04-27 | — | — | US | disclosed |