SCHEMBL30207

SCHEMBL30207

c1ccc(-c2ncon2)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
MAPK1 P28482 1/20 0.46
NR1H4 Q96RI1 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
ADORA2A P29274 6/20 0.43
ADORA1 P30542 6/20 0.43
NOTUM Q6P988 2/20 0.42
GPR55 Q9Y2T6 1/20 0.39
KAT6A Q92794 1/20 0.39
KMO O15229 1/20 0.39
POLB P06746 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
ADORA2B P29275 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28481167 0.96 RAB9A (0.46) PPARANPC1RAB9AMAPK1NR1H4
SCHEMBL17984217 0.86 GP6 (0.44) PPARANPC1RAB9ASMN1; SMN2NFKB1
SCHEMBL17984215 0.83 GPR55 (0.47) PPARANPC1RAB9AMAPK1NR1H4
SCHEMBL4760887 0.81 PPARA (0.48) PPARANPC1RAB9ASMN1; SMN2NFKB1
SCHEMBL2670725 0.79 PPARA (0.45) PPARANPC1RAB9ASMN1; SMN2NFKB1
SCHEMBL19835665 0.78 RAB9A (0.44) PPARANPC1RAB9AADORA2AADORA1
SCHEMBL19356875 0.77 KMO (0.40) PPARAADORA2AADORA1KMO
SCHEMBL6854121 0.77 NPC1 (0.43) PPARANPC1RAB9AMAPK1NR1H4
SCHEMBL70247 0.77 RAB9A (0.48) PPARANPC1RAB9ASMN1; SMN2KMO
SCHEMBL3398203 0.77 KMO (0.47) NPC1RAB9AMAPK1NR1H4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151705-A1 NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY VRISE THERAPEUTICS, INC. (US) 2025-07-17 WO claimed
EP-4250926-A1 AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI Industries Ltd. (IN) 2023-10-04 EP claimed
CN-113214242-B Compound with mother nucleus of 3-phenyl-1, 2, 4-oxadiazole and preparation method and application thereof 中国药科大学 2022-09-20 CN claimed
WO-2022113033-A1 AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-06-02 WO claimed
CN-113214242-A Compound with mother nucleus of 3-phenyl-1, 2, 4-oxadiazole and preparation method and application thereof 中国药科大学 2021-08-06 CN claimed
CN-111138376-A 3, 5-disubstituted phenyl-1, 2, 4-oxadiazole derivative and preparation method and application thereof 中山大学 2020-05-12 CN claimed
CN-110337293-A Therapeutic compound 新泽西鲁特格斯州立大学 2019-10-15 CN claimed
CN-110305072-A Compound and its application with phosphodiesterase 4 D and acid sphingomyelinase inhibitory activity 中国药科大学 2019-10-08 CN claimed
CN-110156769-A Compound and its preparation method and application with xanthine oxidase inhibitory activity 沈阳海诺威医药科技有限公司 2019-08-23 CN claimed
CN-106146487-B Pyridylmethyl dithiocarbonic acid hetero-aromatic ring alkyl esters compound and its preparation method and application 北京大学 2019-05-10 CN claimed
US-6166023-A 1,5- and 3-O-substituted 1H-indazoles having anti-asthmatic, anti-allergic, anti-inflammatory, immunomodulating and neuroprotective action, process for their preparation and their use as medicaments ARZNEIMITTELWERK DRESDEN GMBH (DE) 2000-12-26 US claimed
WO-1999058504-A9 NOVEL 1,2,5-TRISUBSTITUTED 1,2-DIHYDRO-INDAZOL-3-ONES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS A MEDICAMENT DRESDEN ARZNEIMITTEL (DE) 2000-02-03 WO claimed
WO-1999058504-A1 NOVEL 1,2,5-TRISUBSTITUTED 1,2-DIHYDRO-INDAZOL-3-ONES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS A MEDICAMENT ARZNEIMITTELWERK DRESDEN GMBH (DE) 1999-11-18 WO claimed
WO-1999058503-A1 NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS ARZNEIMITTELWERK DRESDEN GMBH (DE) 1999-11-18 WO claimed
CN-1201456-A Novel cyclic depsipeptide PF1022 derivatives MEIJI SEIKA CO (JP) 1998-12-09 CN claimed
EP-0401981-B1 Pyridazinone deriratives PFIZER (US) 1995-04-26 EP claimed
EP-0305197-B1 METHOD FOR MAKING A GRAPHITE FILM OR SHEET AND RADIATION OPTICAL ELEMENTS USING THE GRAPHITE SHEET MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-06-03 EP claimed
US-4996204-A Antidiabetic agents PFIZER INC. (US) 1991-02-26 US claimed
US-4954193-A HIGH TEMPERATURE HOT PRESSING POLYOXADIAZOLOE, AROMATIC POLYIMIDE, AND POLYAMIDE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-09-04 US claimed
EP-0305197-A2 Method for making a graphite film or sheet and radiation optical elements using the graphite sheet MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1989-03-01 EP claimed