SCHEMBL173367

SCHEMBL173367

Cc1ccc(-c2cc(N)ccc2N)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.50
ALDH1A1 P00352 7/20 0.46
NPC1 O15118 5/20 0.46
RAB9A P51151 5/20 0.46
TSHR P16473 3/20 0.46
CASP1 P29466 3/20 0.46
HSD17B10 Q99714 3/20 0.46
CASP7 P55210 2/20 0.46
TDP1 Q9NUW8 4/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
TP53 P04637 3/20 0.44
CYP3A4 P08684 2/20 0.44
THRB P10828 1/20 0.44
ALOX15 P16050 1/20 0.44
MAPT P10636 4/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 2/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29938910 1.00 ACHE (0.50) ACHEALDH1A1NPC1RAB9ATSHR
Hydrochloric Acid SCHEMBL6574550 0.98 ACHE (0.48) ACHEALDH1A1NPC1RAB9ATSHR
SCHEMBL4597146 0.88 ACHE (0.52) ACHEALDH1A1NPC1RAB9ATSHR
SCHEMBL3803718 0.87 TDP1 (0.50) ACHEALDH1A1NPC1RAB9ATSHR
SCHEMBL10713204 0.86 TDP1 (0.54) ACHEALDH1A1NPC1RAB9ATSHR
SCHEMBL2479814 0.86 TDP1 (0.50) ALDH1A1NPC1RAB9ATSHRCASP1
SCHEMBL30075769 0.86 TDP1 (0.50) ALDH1A1NPC1RAB9ATSHRCASP1
SCHEMBL28543486 0.84 CASP1 (0.44) ACHEALDH1A1NPC1RAB9ATSHR
SCHEMBL22517453 0.84 TDP1 (0.50) ACHEALDH1A1NPC1RAB9ATSHR
SCHEMBL5851572 0.84 ACHE (0.52) ACHEALDH1A1NPC1RAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117643307-A Hypochlorous acid-containing disinfectant and preparation method thereof 南京昊宇通医药科技有限公司 2024-03-05 CN claimed
CN-116589761-A Environment-friendly sole material and preparation method thereof 薛天翔 2023-08-15 CN claimed
CN-115856042-A Photoelectric sensor based on ultrathin two-dimensional covalent organic nanosheet/MXene composite material, and preparation method and application thereof 德清县浙工大莫干山研究院 2023-03-28 CN claimed
CN-109689792-B Liquid antioxidant composition for raw rubber 巴斯夫欧洲公司 2022-03-29 CN claimed
CN-109148926-A flow battery 松下知识产权经营株式会社 2019-01-04 CN claimed
CN-107686606-A A kind of ceramic high-heat-resistant conveyer belt and preparation method thereof 保定三源橡胶有限公司 2018-02-13 CN claimed
CN-105255206-B A kind of warm mix regeneration asphalt and preparation method thereof 长安大学 2017-11-14 CN claimed
EP-2611797-A2 QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS Hanmi Science Co., Ltd. (KR) 2013-07-10 EP claimed
WO-2012030160-A2 QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS HANMI HOLDINGS CO., LTD. (KR) 2012-03-08 WO claimed
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP claimed
EP-1276804-A1 LIQUID ANTIOZONANTS AND RUBBER COMPOSITIONS CONTAINING SAME Uniroyal Chemical Company, Inc. (US) 2003-01-22 EP claimed
US-6500213-B1 Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives WELLA AKTIENGESELLSCHAFT (DE) 2002-12-31 US claimed
WO-2001081459-A1 LIQUID ANTIOZONANTS AND RUBBER COMPOSITIONS CONTAINING SAME UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-11-01 WO claimed
EP-1051143-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES Wella Aktiengesellschaft (DE) 2000-11-15 EP claimed
WO-1999059527-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO claimed
JP-54153851-A None JP disclosed
CN-118085584-A Tear-resistant fluorosilicone rubber compound and preparation method thereof 温州合丰胶业股份有限公司 2024-05-28 CN disclosed
WO-1997024108-A1 HAIR BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
WO-1997024107-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
JP-S54153851-A ANTIOXIDANT OF RUBBER BRIDGESTONE CORP 1979-12-04 JP disclosed