Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.53 |
| ▸ | PIK3R2 | O00459 | 18/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17338208 | 0.96 | PIK3CD (0.52) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338267 | 0.91 | PIK3CD (0.49) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338253 | 0.88 | PIK3CD (0.51) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338324 | 0.88 | PIK3CD (0.49) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338191 | 0.88 | PIK3R2 (0.52) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338218 | 0.87 | PIK3CD (0.49) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338250 | 0.86 | PIK3CD (0.48) | PIK3CDPIK3R2 | |
| SCHEMBL17330871 | 0.84 | PIK3CD (0.73) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338316 | 0.84 | PIK3CD (0.50) | PIK3CDPIK3R2 | |
| SCHEMBL17330870 | 0.84 | PIK3CD (0.73) | PIK3CDPIK3R2PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154958-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015191752-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2015-12-17 | — | — | WO | disclosed |