Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28608967 | 0.87 | F3 (0.56) | NNMTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL30034522 | 0.85 | P4HTM (0.58) | NNMTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL1124610 | 0.85 | P4HTM (0.58) | NNMTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL1124609 | 0.85 | P4HTM (0.58) | NNMTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL28609817 | 0.85 | GSK3B (0.60) | NPC1RAB9ALMNASMN1; SMN2MAPT | |
| SCHEMBL20139654 | 0.85 | P4HTM (0.58) | NNMTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL14480283 | 0.85 | NNMT (0.59) | NNMTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL8664417 | 0.84 | FDPS (0.58) | NPC1RAB9ALMNASMN1; SMN2MAPT | |
| SCHEMBL8664419 | 0.84 | FDPS (0.58) | NPC1RAB9ALMNASMN1; SMN2MAPT | |
| SCHEMBL10756396 | 0.83 | NPC1 (0.59) | NNMTNPC1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015188777-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2015-12-17 | — | — | WO | disclosed |