SCHEMBL1733973

SCHEMBL1733973

C1COC(COOCC2CCCO2)C1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
POLB P06746 1/20 0.52
ALDH1A1 P00352 2/20 0.48
TSHR P16473 2/20 0.39
KDM4E B2RXH2 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
USP2 O75604 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TP53 P04637 1/20 0.37
HPGD P15428 1/20 0.37
ALOX12 P18054 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27836154 0.89 LMNA (0.44) LMNAPOLBALDH1A1TSHRKDM4E
SCHEMBL10831463 0.89 LMNA (0.49) LMNAPOLBALDH1A1SMN1; SMN2USP2
SCHEMBL26770040 0.86
SCHEMBL14504871 0.86
SCHEMBL28002446 0.86 LMNA (0.38) LMNAPOLBALDH1A1TSHRSMN1; SMN2
SCHEMBL3678357 0.84 LMNA (0.49) LMNAPOLBALDH1A1TSHRKDM4E
SCHEMBL812840 0.84 LMNA (0.52) LMNAPOLBALDH1A1TSHRSMN1; SMN2
SCHEMBL3757540 0.82 LMNA (0.50) LMNAPOLBALDH1A1TSHRSMN1; SMN2
Barium SCHEMBL2592652 0.82 LMNA (0.50) LMNAPOLBALDH1A1TSHRSMN1; SMN2
SCHEMBL16345225 0.82 LMNA (0.50) LMNAPOLBALDH1A1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1033128-B1 Soft gelatin capsule manufacture SCHERER GMBH R P (DE) 2008-06-18 EP claimed
EP-1033128-A2 Soft gelatin capsule manufacture R.P. Scherer GmbH (DE) 2000-09-06 EP claimed
EP-1029538-A2 Soft gelatin capsule manufacture R.P. Scherer GmbH (DE) 2000-08-23 EP claimed
EP-0649651-A1 Soft gelatin capsule manufacture R.P. Scherer GmbH (DE) 1995-04-26 EP claimed
CN-116581400-A Eutectic electrolyte of zinc ion secondary battery, zinc ion secondary battery and preparation method 福州大学 2023-08-11 CN disclosed
CN-109796427-A A kind of preparation method of tetrahydrofurfuryl alcohol 华东师范大学 2019-05-24 CN disclosed
EP-1033128-B2 Soft gelatin capsule manufacture SCHERER GMBH R P (DE) 2011-11-23 EP disclosed
WO-2011132623-A1 NOVEL NAPHTHOTHIOPHENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-10-27 WO disclosed
EP-1033128-B1 Soft gelatin capsule manufacture SCHERER GMBH R P (DE) 2008-06-18 EP disclosed
EP-1033128-A2 Soft gelatin capsule manufacture R.P. Scherer GmbH (DE) 2000-09-06 EP disclosed
EP-1029538-A2 Soft gelatin capsule manufacture R.P. Scherer GmbH (DE) 2000-08-23 EP disclosed