SCHEMBL17343147

SCHEMBL17343147

Clc1ccc2c(-c3ccccc3)nccc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.51
NPSR1 Q6W5P4 4/20 0.51
KMT2A Q03164 3/20 0.51
CASP1 P29466 2/20 0.51
MEN1 O00255 1/20 0.51
HSD17B10 Q99714 1/20 0.51
MAP4K4 O95819 1/20 0.49
MAPT P10636 3/20 0.45
LMNA P02545 3/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
L3MBTL1 Q9Y468 3/20 0.44
GAA P10253 2/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
GPR55 Q9Y2T6 1/20 0.44
MAT2A P31153 1/20 0.44
PDE3B Q13370 2/20 0.44
PDE3A Q14432 2/20 0.44
GLA P06280 1/20 0.44
SCN9A Q15858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28191720 0.82 MAP4K4 (0.47) KDM4ENPSR1KMT2ACASP1HSD17B10
SCHEMBL20995827 0.80 MAP4K4 (0.40) KMT2AMEN1MAP4K4PDE3BPDE3A
SCHEMBL29738160 0.80 MAP4K4 (0.40) KMT2AMEN1MAP4K4PDE3BPDE3A
SCHEMBL17343157 0.80 GCGR (0.44) KDM4EKMT2AMAP4K4PDE3BPDE3A
SCHEMBL4443976 0.79 BCHE (0.52) KDM4ENPSR1KMT2ACASP1MEN1
SCHEMBL15712766 0.79 ESR1 (0.46) KDM4ENPSR1KMT2AMEN1MAPT
SCHEMBL17299585 0.79 IDO1 (0.54) KDM4ENPSR1KMT2ACASP1HSD17B10
SCHEMBL15124248 0.78 KDM4E (0.45) KDM4ENPSR1KMT2ACASP1MEN1
SCHEMBL30576396 0.78 KDM4E (0.45) KDM4ENPSR1KMT2ACASP1MEN1
SCHEMBL29398625 0.77 KDM4E (0.66) KDM4ENPSR1KMT2ACASP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10636982-B2 Iridium complex and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2020-04-28 US disclosed
US-9601704-B2 Organic light-emitting device and display apparatus CANON KABUSHIKI KAISHA (JP) 2017-03-21 US disclosed
US-9601704-B2 Organic light-emitting device and display apparatus CANON KABUSHIKI KAISHA (JP) 2017-03-21 US disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150364702-A1 IRIDIUM COMPLEX AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed
US-20150364702-A1 IRIDIUM COMPLEX AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed
US-20150364703-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed
US-20150364703-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10636982-B2 Iridium complex and organic light-emitting device including the same MAP1LC3C, MAP1LC3B, MAP1LC3A KDM4E 3661/4885NPSR1 4008/4885KMT2A 1864/4885
US-20150364702-A1 IRIDIUM COMPLEX AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME MAP1LC3C, MAP1LC3B, MAP1LC3A KDM4E 3661/4885NPSR1 4008/4885KMT2A 1864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.