Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 5/20 | 0.49 |
| ▸ | TUBB | P07437 | 5/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.49 |
| ▸ | CD74 | P04233 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809262 | 0.90 | CD74 (0.48) | CD74MIFGSK3BCYP19A1FLT3 | |
| SCHEMBL1733372 | 0.90 | TEK (0.46) | GSK3BCYP19A1FLT3MEN1KMT2A | |
| SCHEMBL1734203 | 0.85 | CD74 (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1734185 | 0.81 | CYP19A1 (0.51) | GSK3BCYP19A1FLT3MEN1KMT2A | |
| SCHEMBL1809812 | 0.81 | CD74 (0.53) | CD74MIFCYP19A1GPR55MEN1 | |
| SCHEMBL510232 | 0.80 | BTK (0.53) | TRPV6MEN1KMT2AL3MBTL1ROCK1 | |
| SCHEMBL1805271 | 0.78 | CCNK (0.56) | CYP19A1MEN1KMT2ACCNKCDK12 | |
| SCHEMBL1735279 | 0.78 | RAB9A (0.44) | TRPV6L3MBTL1ROCK1FAAHMGLL | |
| SCHEMBL1733697 | 0.78 | CD74 (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1805789 | 0.77 | MAOB (0.49) | GSK3BCYP19A1CCNKCDK12JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183264-B2 | Pyridine derivative substituted by heteroaryl ring, and antifungal agent comprising the same | Eisai R&D Managment Co., Ltd. (JP) | 2012-05-22 | — | — | US | claimed |
| US-8183264-B2 | Pyridine derivative substituted by heteroaryl ring, and antifungal agent comprising the same | Eisai R&D Managment Co., Ltd. (JP) | 2012-05-22 | — | — | US | disclosed |
| US-8183264-B2 | Pyridine derivative substituted by heteroaryl ring, and antifungal agent comprising the same | Eisai R&D Managment Co., Ltd. (JP) | 2012-05-22 | — | — | US | disclosed |
| US-8183264-B2 | Pyridine derivative substituted by heteroaryl ring, and antifungal agent comprising the same | Eisai R&D Managment Co., Ltd. (JP) | 2012-05-22 | — | — | US | disclosed |
| EP-2065377-B1 | PYRIDINE DERIVATIVE SUBSTITUTED BY HETEROARYL RING, AND ANTIFUNGAL AGENT COMPRISING THE SAME | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-18 | — | — | US | disclosed |
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2345328-A1 | COMPOSITION FOR AGRICULTURAL USE | Sumitomo Chemical Company, Limited (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-20100099718-A1 | PYRIDINE DERIVATIVE SUBSTITUTED BY HETEROARYL RING, AND ANTIFUNGAL AGENT COMPRISING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20100099718-A1 | PYRIDINE DERIVATIVE SUBSTITUTED BY HETEROARYL RING, AND ANTIFUNGAL AGENT COMPRISING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20100099718-A1 | PYRIDINE DERIVATIVE SUBSTITUTED BY HETEROARYL RING, AND ANTIFUNGAL AGENT COMPRISING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| EP-2065377-A1 | PYRIDINE DERIVATIVE SUBSTITUTED BY HETEROARYL RING, AND ANTIFUNGAL AGENT COMPRISING THE SAME | Eisai R&D Management Co., Ltd. (JP) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | H1-0, H1-3, H1-2 | TUBB4A 3334/4885TUBB 1975/4885TUBA3C 1370/4885 |
| US-20100099718-A1 | PYRIDINE DERIVATIVE SUBSTITUTED BY HETEROARYL RING, AND ANTIFUNGAL AGENT COMPRISING THE SAME | ERG28, CBR3, CBR1 | TUBB4A 752/4885TUBB 341/4885TUBA3C 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.