SCHEMBL173444

SCHEMBL173444

CCC(OC(C)=O)c1ccccc1N(c1ccccc1)c1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 1/20 0.37
MAPT P10636 3/20 0.35
KCNH2 Q12809 1/20 0.35
ALDH1A1 P00352 4/20 0.34
LMNA P02545 1/20 0.34
PABPC1 P11940 1/20 0.34
APOBEC3A P31941 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
GPR88 Q9GZN0 1/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
HPGD P15428 1/20 0.33
KDM4E B2RXH2 1/20 0.33
USP2 O75604 1/20 0.33
GLA P06280 1/20 0.33
TSHR P16473 1/20 0.33
SLC18A3 Q16572 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162266 0.79 PABPC1 (0.45) KCNH2ALDH1A1PABPC1APOBEC3AAPOBEC3G
SCHEMBL8531953 0.73 TSHR (0.46) MAPTALDH1A1LMNAKDM4ETSHR
SCHEMBL14136464 0.72 UTS2R (0.37) MAPTALDH1A1
SCHEMBL8936346 0.71 CYP1A2 (0.36) MAPTALDH1A1LMNAHPGDKDM4E
SCHEMBL7353138 0.70 PTGS2 (0.46) ALDH1A1LMNAHPGDKDM4ETSHR
SCHEMBL9608808 0.69 PABPC1 (0.55) KCNH2ALDH1A1LMNAPABPC1APOBEC3A
SCHEMBL664962 0.69 PABPC1 (0.55) KCNH2ALDH1A1LMNAPABPC1APOBEC3A
SCHEMBL19847573 0.68 CA1 (0.36) MAPTALDH1A1LMNAHPGDKDM4E
Ammonia Solution, Strong SCHEMBL9844915 0.68 PABPC1 (0.54) KCNH2ALDH1A1LMNAPABPC1APOBEC3A
SCHEMBL13777910 0.67 HCAR2 (0.45) MMP12KCNH2ALDH1A1SLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130170016-A1 PHOTOREFRACTIVE DEVICE CONTAINING A CHROMOPHORE-DOPED POLYMER LAYER AND ITS MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2013-07-04 US disclosed
US-20130163086-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE BY UTILIZING ELECTROLYTES NITTO DENKO CORPORATION (JP) 2013-06-27 US disclosed
US-20130128339-A1 PHOTOREFRACTIVE COMPOSITION RESPONSIVE TO MULTIPLE LASER WAVELENGTHS ACROSS THE VISIBLE LIGHT SPECTRUM NITTO DENKO CORPORATION (JP) 2013-05-23 US disclosed
US-20120275007-A1 OPTICAL DEVICES FOR MODULATING LIGHT OF PHOTOREFRACTIVE COMPOSITIONS WITH THERMAL CONTROL NITTO DENKO CORPORATION (JP) 2012-11-01 US disclosed
US-8203780-B2 Systems and methods for improving the performance of a photorefractive device NITTO DENKO CORPORATION (JP) 2012-06-19 US disclosed
US-20120058418-A1 THREE-DIMENSIONAL HOLOGRAPHIC DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2012-03-08 US disclosed
US-20110262845-A1 METHOD FOR MODULATING LIGHT OF PHOTOREFRACTIVE COMPOSITION WITHOUT EXTERNAL BIAS VOLTAGE NITTO DENKO CORPORATION 2011-10-27 US disclosed
US-7985356-B2 Non-linear optical device sensitive to green laser NITTO DENKO CORPORATION (JP) 2011-07-26 US disclosed
WO-2010141323-A1 THREE-DIMENSIONAL HOLOGRAPHIC DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2010-12-09 WO disclosed
US-7736548-B2 Non-linear optical device with long grating persistency NITTO DENKO CORPORATION (JP) 2010-06-15 US disclosed
US-20100099789-A1 METHOD FOR MODULATING LIGHT OF PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORPORATION (JP) 2010-04-22 US disclosed
US-20100096603-A1 OPTICAL DEVICES RESPONSIVE TO NEAR INFRARED LASER AND METHODS OF MODULATING LIGHT NITTO DENKO CORPORATION (JP) 2010-04-22 US disclosed
US-20100060975-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE NITTO DENKO CORPORATION (JP) 2010-03-11 US disclosed
US-20090197186-A1 OPTICAL DEVICES RESPONSIVE TO BLUE LASER AND METHOD OF MODULATING LIGHT NITTO DENKO CORPORATION (JP) 2009-08-06 US disclosed
US-20090092746-A1 PHOTOREFRACTIVE COMPOSITIONS WITH NANOPARTICLES NITTO DENKO CORPORATION (JP) 2009-04-09 US disclosed
US-20090052009-A1 NON-LINEAR OPTICAL DEVICE SENSITIVE TO GREEN LASER NITTO DENKO CORPORATION (JP) 2009-02-26 US disclosed
US-20080039603-A1 NON-LINEAR OPTICAL DEVICE WITH LONG GRATING PERSISTENCY NITTO DENKO CORPORATION (JP) 2008-02-14 US disclosed
US-20060235163-A1 Photorefractive composition NITTO DENKO CORPORATION (JP) 2006-10-19 US disclosed
US-20050051758-A1 Polysiloxane with pendant triphenylamine groups; photoconductive (charge transport) and non-linear optical ability; sensitizers, plasticizers NITTO DENKO CORPORATION (JP) 2005-03-10 US disclosed
US-6653421-B1 Addition copolymer with pendant carbazole and/or triphenylamine groups; photoconductive (charge transport) and non-linear optical ability; sensitizers, plasticizers NITTO DENKO CORPORATION (JP) 2003-11-25 US disclosed