Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16746129 | 0.84 | MMP12 (0.43) | NR3C2MMP12PARP1ADRB1SMN1; SMN2 | |
| SCHEMBL17348473 | 0.80 | NR3C2 (0.57) | NR3C2MMP12PARP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8306404 | 0.79 | NR3C2 (0.47) | NR3C2MMP12PARP1ADRB1SMN1; SMN2 | |
| SCHEMBL6432532 | 0.79 | NR3C2 (0.56) | NR3C2MMP12PARP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24776150 | 0.78 | NR3C2 (0.52) | NR3C2MMP12PARP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15052400 | 0.78 | NR3C2 (0.55) | NR3C2MMP12PARP1ADRB1ALDH1A1 | |
| SCHEMBL3489583 | 0.78 | NR3C2 (0.55) | NR3C2MMP12PARP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22803133 | 0.75 | NR3C2 (0.52) | NR3C2MMP12PARP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24775935 | 0.75 | NR3C2 (0.52) | NR3C2MMP12PARP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15052476 | 0.75 | NR3C2 (0.52) | NR3C2MMP12PARP1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150361093-A1 | HIV REPLICATION INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150361093-A1 | HIV REPLICATION INHIBITOR | RTF2, REV1, PCNA | NR3C2 2947/4885MMP12 3816/4885PARP1 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.