SCHEMBL17345458

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18807122	0.93	STAT3 (0.50)	STAT3ALDH1A1NPC1RAB9AATM
	SCHEMBL18691818	0.91	STAT3 (0.53)	STAT3ALDH1A1NPC1RAB9AATM
	SCHEMBL17345574	0.91	STAT3 (0.48)	STAT3ALDH1A1NPC1RAB9AATM
	SCHEMBL18730828	0.90	STAT3 (0.52)	STAT3ALDH1A1NPC1RAB9AATM
	SCHEMBL17345459	0.90	STAT3 (0.50)	STAT3ALDH1A1NPC1RAB9AATM
	SCHEMBL17345558	0.87	STAT3 (0.49)	STAT3ALDH1A1NPC1RAB9AATM
	SCHEMBL18730810	0.87	STAT3 (0.45)	STAT3ALDH1A1PTPRCLMNASMN1; SMN2
	SCHEMBL17345566	0.87	STAT3 (0.45)	STAT3ALDH1A1PTPRCLMNASMN1; SMN2
	SCHEMBL17345561	0.86	STAT3 (0.48)	STAT3ALDH1A1NPC1RAB9AATM
	SCHEMBL17345512	0.86	STAT3 (0.55)	STAT3ALDH1A1NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.