SCHEMBL18691818

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18730828	0.92	STAT3 (0.52)	STAT3ALDH1A1PTPRCMAPTSMN1; SMN2
	SCHEMBL17345458	0.91	STAT3 (0.51)	STAT3ALDH1A1PTPRCMAPTSMN1; SMN2
	SCHEMBL18807122	0.90	STAT3 (0.50)	STAT3ALDH1A1PTPRCMAPTSMN1; SMN2
	SCHEMBL17345558	0.89	STAT3 (0.49)	STAT3ALDH1A1PTPRCMAPTSMN1; SMN2
	SCHEMBL17345574	0.88	STAT3 (0.48)	STAT3ALDH1A1PTPRCMAPTSMN1; SMN2
	SCHEMBL17345459	0.87	STAT3 (0.50)	STAT3ALDH1A1PTPRCMAPTSMN1; SMN2
	SCHEMBL17345553	0.87	STAT3 (0.60)	STAT3ALDH1A1MAPTSMN1; SMN2LMNA
	SCHEMBL17345512	0.86	STAT3 (0.55)	STAT3ALDH1A1MAPTSMN1; SMN2LMNA
	SCHEMBL18730810	0.85	STAT3 (0.45)	STAT3ALDH1A1PTPRCMAPTSMN1; SMN2
	SCHEMBL17345566	0.85	STAT3 (0.45)	STAT3ALDH1A1PTPRCMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.