Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18730810 | 1.00 | STAT3 (0.45) | STAT3ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL17345459 | 0.89 | STAT3 (0.50) | STAT3ALDH1A1PTPRCAPAF1MITF | |
| SCHEMBL17345574 | 0.88 | STAT3 (0.48) | STAT3ALDH1A1PTPRCAPAF1MITF | |
| SCHEMBL17345458 | 0.87 | STAT3 (0.51) | STAT3ALDH1A1PTPRCAPAF1MITF | |
| SCHEMBL18807122 | 0.86 | STAT3 (0.50) | STAT3ALDH1A1PTPRCAPAF1MITF | |
| SCHEMBL17345430 | 0.85 | STAT3 (0.51) | STAT3ALDH1A1PTPRCAPAF1MITF | |
| SCHEMBL18691818 | 0.85 | STAT3 (0.53) | STAT3ALDH1A1PTPRCAPAF1MITF | |
| SCHEMBL17345471 | 0.84 | STAT3 (0.52) | STAT3ALDH1A1APAF1MITFLMNA | |
| SCHEMBL18730828 | 0.84 | STAT3 (0.52) | STAT3ALDH1A1PTPRCAPAF1MITF | |
| SCHEMBL17345493 | 0.82 | STAT3 (0.50) | STAT3ALDH1A1PTPRCAPAF1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015190489-A1 | NOVEL ANTICANCER AGENT | 京都薬品工業株式会社 | 2015-12-17 | — | — | WO | disclosed |