Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 5/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18691828 | 0.88 | ALDH1A1 (0.59) | STAT3ALDH1A1PTPN1APAF1LMNA | |
| SCHEMBL18731215 | 0.88 | STAT3 (0.59) | STAT3ALDH1A1PTPRCPTPN1APAF1 | |
| SCHEMBL29448088 | 0.88 | STAT3 (0.59) | STAT3ALDH1A1PTPRCPTPN1APAF1 | |
| SCHEMBL17345498 | 0.87 | STAT3 (0.56) | STAT3ALDH1A1PTPN1APAF1LMNA | |
| SCHEMBL18691820 | 0.86 | STAT3 (0.57) | STAT3ALDH1A1APAF1LMNAMAPT | |
| SCHEMBL17345553 | 0.86 | STAT3 (0.60) | STAT3ALDH1A1APAF1LMNAMAPT | |
| SCHEMBL18807113 | 0.86 | STAT3 (0.57) | STAT3ALDH1A1APAF1LMNAMAPT | |
| SCHEMBL18691822 | 0.85 | STAT3 (0.56) | STAT3ALDH1A1APAF1LMNAMAPT | |
| SCHEMBL18730823 | 0.85 | STAT3 (0.56) | STAT3ALDH1A1APAF1LMNAMAPT | |
| SCHEMBL17345513 | 0.85 | STAT3 (0.59) | STAT3ALDH1A1APAF1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153508-A1 | NOVEL ANTICANCER AGENT | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2017-04-12 | — | — | EP | disclosed |
| WO-2015190489-A1 | NOVEL ANTICANCER AGENT | 京都薬品工業株式会社 | 2015-12-17 | — | — | WO | disclosed |