SCHEMBL18691828

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18730814	0.93	STAT3 (0.52)	ALDH1A1STAT3MAPTLMNASMN1; SMN2
	SCHEMBL17345532	0.92	ALDH1A1 (0.53)	ALDH1A1STAT3MAPTLMNASMN1; SMN2
	SCHEMBL18807113	0.90	STAT3 (0.57)	ALDH1A1STAT3MAPTLMNASMN1; SMN2
	SCHEMBL17345519	0.89	STAT3 (0.53)	ALDH1A1STAT3MAPTLMNASMN1; SMN2
	SCHEMBL18730823	0.89	STAT3 (0.56)	ALDH1A1STAT3MAPTLMNASMN1; SMN2
	SCHEMBL17345518	0.89	ALDH1A1 (0.50)	ALDH1A1STAT3MAPTLMNASMN1; SMN2
	SCHEMBL17345477	0.88	STAT3 (0.64)	ALDH1A1STAT3MAPTLMNASMN1; SMN2
	SCHEMBL18807118	0.88	STAT3 (0.54)	ALDH1A1STAT3MAPTLMNASMN1; SMN2
	SCHEMBL18691820	0.88	STAT3 (0.57)	ALDH1A1STAT3MAPTLMNASMN1; SMN2
	SCHEMBL17345553	0.88	STAT3 (0.60)	ALDH1A1STAT3MAPTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.