SCHEMBL17346100

SCHEMBL17346100

CCCN(CCNCCCSc1ccccc1)Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 3/20 0.46
DRD4 P21917 3/20 0.46
DRD3 P35462 2/20 0.46
FDPS P14324 1/20 0.43
BCHE P06276 3/20 0.41
HRH3 Q9Y5N1 1/20 0.41
ACKR3 P25106 2/20 0.40
SIGMAR1 Q99720 1/20 0.40
RORC P51449 2/20 0.40
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17346001 0.94 DRD2 (0.45) DRD2DRD4DRD3FDPSBCHE
SCHEMBL17346025 0.91 DRD3 (0.47) DRD2DRD4DRD3FDPSBCHE
SCHEMBL17345999 0.90 DRD2 (0.51) DRD2DRD4DRD3FDPSKMT2A
SCHEMBL17345997 0.88 DRD2 (0.49) DRD2DRD4DRD3FDPSKMT2A
SCHEMBL17346030 0.86 DRD2 (0.48) DRD2DRD4DRD3FDPSSIGMAR1
SCHEMBL17346006 0.85 BCHE (0.49) BCHEHRH3ACKR3RORCALDH1A1
SCHEMBL17346000 0.83 DRD2 (0.50) DRD2DRD4DRD3FDPSSIGMAR1
SCHEMBL17346391 0.83 SLC2A1 (0.53) DRD2DRD4DRD3FDPSSIGMAR1
SCHEMBL17346307 0.82 ACKR3 (0.54) DRD2DRD4DRD3FDPSACKR3
SCHEMBL17346008 0.81 DRD2 (0.48) DRD2DRD4DRD3FDPSSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10550139-B2 Polydentate ligands and their complexes for molecular catalysis TRIAD NATIONAL SECURITY, LLC (US) 2020-02-04 US disclosed
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS TRIAD NATIONAL SECURITY, LLC 2017-03-30 US disclosed
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS TRIAD NATIONAL SECURITY, LLC 2017-03-30 US disclosed
WO-2015191505-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS LOS ALAMOS NATIONAL SECURITY, LLC (US) 2015-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS NANS, NCL, NCLN DRD2 501/4885DRD4 243/4885DRD3 455/4885
US-10550139-B2 Polydentate ligands and their complexes for molecular catalysis NANS, NCL, NCLN DRD2 501/4885DRD4 243/4885DRD3 455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.