SCHEMBL17346183

SCHEMBL17346183

CN(C)CCCN(CCCSCc1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.44
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
CYP2C19 P33261 2/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.37
NPY2R P49146 2/20 0.37
HTR2A P28223 1/20 0.37
HRH1 P35367 1/20 0.37
AOC3 Q16853 1/20 0.37
PIM1 P11309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17346323 0.94 SIGMAR1 (0.44) SIGMAR1POLBTDP1TAAR1CYP2C19
SCHEMBL17346112 0.86 SIGMAR1 (0.47) SIGMAR1TAAR1CYP2C19CYP1A2CYP3A4
SCHEMBL17346426 0.84 TAAR1 (0.43) SIGMAR1POLBTDP1TAAR1CYP2C19
SCHEMBL17346204 0.82 HTT (0.47) SIGMAR1TAAR1CYP2C19CYP1A2CYP3A4
SCHEMBL17346325 0.81 TSHR (0.41) SIGMAR1POLBTDP1CYP2C19CYP1A2
SCHEMBL17345919 0.81 HTR2A (0.41) SIGMAR1TAAR1ALDH1A1HTR2AHRH1
SCHEMBL17345900 0.80 SIGMAR1 (0.47) SIGMAR1TAAR1CYP2C19CYP1A2CYP3A4
SCHEMBL24244319 0.78 TAAR1 (0.54) SIGMAR1POLBTDP1TAAR1CYP2C19
SCHEMBL17346233 0.77 SIGMAR1 (0.45) SIGMAR1TAAR1
SCHEMBL17346199 0.76 SIGMAR1 (0.43) SIGMAR1POLBTDP1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10550139-B2 Polydentate ligands and their complexes for molecular catalysis TRIAD NATIONAL SECURITY, LLC (US) 2020-02-04 US disclosed
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS TRIAD NATIONAL SECURITY, LLC 2017-03-30 US disclosed
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS TRIAD NATIONAL SECURITY, LLC 2017-03-30 US disclosed
WO-2015191505-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS LOS ALAMOS NATIONAL SECURITY, LLC (US) 2015-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS NANS, NCL, NCLN SIGMAR1 412/4885POLB 399/4885TDP1 2145/4885
US-10550139-B2 Polydentate ligands and their complexes for molecular catalysis NANS, NCL, NCLN SIGMAR1 412/4885POLB 399/4885TDP1 2145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.