Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16358344 | 0.84 | HTT (0.55) | RAB9AHTTLMNAMAPK1CA12 | |
| SCHEMBL31493230 | 0.82 | HTT (1.00) | RAB9AHTTLMNAMAPK1CA12 | |
| SCHEMBL503994 | 0.82 | HTT (1.00) | RAB9AHTTLMNAMAPK1CA12 | |
| SCHEMBL9623610 | 0.81 | LMNA (0.66) | RAB9AHTTLMNAMAPK1CA12 | |
| SCHEMBL229063 | 0.79 | TSHR (0.71) | RAB9AHTTLMNAMAPK1CA12 | |
| SCHEMBL20042919 | 0.79 | HTT (0.64) | RAB9AHTTLMNAMAPK1CA12 | |
| SCHEMBL30147631 | 0.79 | HTT (0.64) | RAB9AHTTLMNAMAPK1CA12 | |
| SCHEMBL30929945 | 0.79 | RAB9A (0.64) | RAB9AHTTLMNAMAPK1CA12 | |
| SCHEMBL30147507 | 0.79 | RAB9A (0.64) | RAB9AHTTLMNAMAPK1CA12 | |
| SCHEMBL12490198 | 0.79 | RAB9A (0.64) | RAB9AHTTLMNAMAPK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2015189901-A1 | HYDANTOIN DERIVATIVE-CONTAINING PHARMACEUTICAL COMPOSITION | 中外製薬株式会社 | 2015-12-17 | — | — | WO | disclosed |
| WO-2015190451-A1 | HYDANTOIN DERIVATIVE-CONTAINING PHARMACEUTICAL COMPOSITION | 中外製薬株式会社 | 2015-12-17 | — | — | WO | disclosed |