Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | SELL | P14151 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132017 | 0.84 | GPR35 (0.69) | GPR35MEN1KMT2AMAPTKDM4E | |
| SCHEMBL31392530 | 0.84 | GPR35 (0.69) | GPR35MEN1KMT2AMAPTKDM4E | |
| SCHEMBL910132 | 0.80 | KDM4E (0.47) | GPR35MEN1KMT2AMAPTKDM4E | |
| SCHEMBL18610015 | 0.76 | TSHR (0.42) | GPR35KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL471443 | 0.74 | KDM4E (0.46) | MEN1KMT2AMAPTKDM4EPOLB | |
| SCHEMBL3659922 | 0.74 | SELL (0.56) | MEN1KMT2AMAPTKDM4EPOLB | |
| SCHEMBL6175983 | 0.72 | CSNK2A1 (0.50) | MEN1KMT2AMAPTKDM4EPOLB | |
| SCHEMBL11712068 | 0.71 | AKR1C2 (0.46) | MEN1KMT2AMAPTKDM4EPOLB | |
| SCHEMBL3661233 | 0.71 | KDM4E (0.54) | MEN1KMT2AMAPTKDM4EPOLB | |
| SCHEMBL909607 | 0.71 | PLAU (0.50) | MEN1KMT2AMAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150364311-A1 | COMPOSITIONS AND METHODS FOR MASS SPECTOMETRY | MSTM, LLC | 2015-12-17 | — | — | US | disclosed |